Provider: Silverchair Database: AmericanMedicalAssociation Content: text/plain; charset="UTF-8" TY - JOUR AU - Iyer, Stuthi AU - Kennedy, Jason N. AU - Jentzer, Jacob C. AU - Senussi, Mourad H. AU - Seymour, Christopher W. T1 - Cardiac Function Before Sepsis and Clinical Outcomes PY - 2024 Y1 - 2024/05/07 DO - 10.1001/jama.2024.3917 JO - JAMA JA - JAMA VL - 331 IS - 17 SP - 1496 EP - 1499 SN - 0098-7484 AB - Between 2009 and 2014, 21% of US adults with sepsis did not survive. Guidelines recommend urgent resuscitation of patients with sepsis, although the ideal treatment regimen is not clear and challenges to resuscitation, including the management of sepsis-related cardiac dysfunction, remain. How preexisting cardiac disease is associated with outcomes is poorly understood. This study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospitalization outcomes and mortality. Y2 - 5/20/2024 UR - https://doi.org/10.1001/jama.2024.3917 ER -