RT Journal Article
A1 Tsang, Jung Yin
A1 Kontopantelis, Evangelos
A1 Ashcroft, Darren M.
T1 Methodological Concerns and Potential Confounding Factors—Reply
JF JAMA Ophthalmology
JO JAMA Ophthalmol
YR 2024
DO 10.1001/jamaophthalmol.2024.1030
SN 2168-6165
AB In Reply We thank Yang and colleagues for their comments in response to our recent publication. We elected to use routinely collected electronic health records to allow a large sample size and the inclusion of a wide range of covariates. These records have been shown to be nationally representative in terms of age, sex, ethnicity, and socioeconomic deprivation. The records were collated from approximately 25% of the UK population, with high validity for diagnostic coding, including fractures, to reduce the impact of selection bias. Indeed, the limitations of this approach have already been stated in our article, including the inability to assess visual function or hospital treatments and a likelihood to report more serious falls requiring medical attention. Yet, other approaches, such as self-reporting of falls in surveys, are subject to recall bias. A deeper assessment into the strengths and limitations of our population-based approach has also been explored in a helpful commentary by Pundlik and Luo.
RD 5/20/2024
UL https://doi.org/10.1001/jamaophthalmol.2024.1030