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  • A Dynamical Systems View of Psychiatric Disorders—Practical Implications: A Review

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    JAMA Psychiatry. 2024; 10.1001/jamapsychiatry.2024.0228

    This narrative review, the second of 2 parts about a new approach to the diagnosis and treatment of psychiatric disorders that is based on dynamical systems theory, describes the implications of evidence for the practical applicability of this theory and its quantitative tools.

  • A Dynamical Systems View of Psychiatric Disorders—Theory: A Review

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    JAMA Psychiatry. 2024; 10.1001/jamapsychiatry.2024.0215

    This narrative review describes a new approach to the diagnosis and treatment of psychiatric disorders that is based on dynamical systems theory, which addresses the concepts of tipping points, cycles, and chaos in complex systems.

  • Continuation of Antidepressants vs Sequential Psychological Interventions to Prevent Relapse in Depression: An Individual Participant Data Meta-analysis

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    JAMA Psychiatry. 2021; 78(8):868-875. 10.1001/jamapsychiatry.2021.0823

    This meta-analysis compares the associations between use of a psychological intervention during tapering of antidepressant medication vs antidepressant medication monotherapy with relapse risk and estimates associations of individual factors with relapse of depression.

  • Effectiveness of Emotional Memory Reactivation vs Control Memory Reactivation Before Electroconvulsive Therapy in Adult Patients With Depressive Disorder: A Randomized Clinical Trial

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    ÁñÁ«ÊÓƵ Netw Open. 2020; 3(8):e2012389. 10.1001/jamanetworkopen.2020.12389

    This randomized clinical trial assesses whether emotional memory retrieval in adult patients before receiving electroconvulsive therapy (ECT) weakens underlying cognitive schemas, improves ECT effectiveness, increases ECT response, and reduces relapse rates.

  • Long-term Outcomes of Cognitive Behavioral Therapy for Anxiety-Related Disorders: A Systematic Review and Meta-analysis

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    JAMA Psychiatry. 2019; 77(3):265-273. 10.1001/jamapsychiatry.2019.3986

    This systematic review and meta-analysis of 69 randomized clinical trials assesses long-term outcomes after cognitive behavioral therapy for anxiety disorders, posttraumatic stress disorder, and obsessive-compulsive disorder.