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JAMA Cardiology
Original Investigation
April 17, 2024
Yi聽Li,聽MD; Jing聽Li,聽MD; Bin聽Wang,聽MD; Quanmin聽Jing,聽MD; Yujie聽Zeng,聽MD; Aijie聽Hou,聽MD; Zhifang聽Wang,聽MD; Aijun聽Liu,聽MD; Jinliang聽Zhang,聽MD; Yaojun聽Zhang,聽MD; Ping聽Zhang,聽MD; Daming聽Jiang,聽MD; Bin聽Liu,聽MD; Jiamao聽Fan,聽MD; Jun聽Zhang,聽MD; Li聽Li,聽MD; Guohai聽Su,聽MD; Ming聽Yang,聽MD; Weihong聽Jiang,聽MD; Peng聽Qu,聽MD; Hesong聽Zeng,聽MD, PhD; Lu聽Li,聽MD; Miaohan聽Qiu,聽MD; Leisheng聽Ru,聽MD; Shaoliang聽Chen,聽MD; Yujie聽Zhou,聽MD; Shubin聽Qiao,聽MD; Gregg W.听Stone,聽MD; Dominick J.听Angiolillo,聽MD, PhD; Yaling聽Han,聽MD; OPT-BIRISK Investigators
online first
JAMA Cardiol. 2024; 10.1001/jamacardio.2024.0534
This randomized clinical trial evaluates clopidogrel monotherapy vs dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions who are at high bleeding and ischemic risk.
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JAMA Cardiology
Original Investigation
March 20, 2024
Marco聽Valgimigli,聽MD, PhD; Felice聽Gragnano,聽MD, PhD; Mattia聽Branca,聽PhD; Anna聽Franzone,聽MD, PhD; Bruno R.听da Costa,聽PhD; Usman聽Baber,聽MD; Takeshi聽Kimura,聽MD; Yangsoo聽Jang,聽MD, PhD; Joo-Yong聽Hahn,聽MD; Qiang聽Zhao,聽MD, PhD; Stephan聽Windecker,聽MD; Charles M.听Gibson,聽MD; Hirotoshi聽Watanabe,聽MD; Byeong-Keuk聽Kim,聽MD; Young Bin聽Song,聽MD; Yunpeng聽Zhu,聽MD; Pascal聽Vranckx,聽MD, PhD; Shamir聽Mehta,聽MD; Kenji聽Ando,聽MD; Sung Jin聽Hong,聽MD; Hyeon-Cheol聽Gwon,聽MD; Patrick W.听Serruys,聽MD; George D.听Dangas,聽MD; E霉gene P.听McFadden,聽MD; Dominick J.听Angiolillo,聽MD, PhD; Dik聽Heg,聽PhD; Paolo聽Calabr貌,聽MD, PhD; Peter聽J眉ni,聽MD; Roxana聽Mehran,聽MD; Single Versus Dual Antiplatelet Therapy (Sidney-3) Collaboration
JAMA Cardiol. 2024; 9(5):437-448. 10.1001/jamacardio.2024.0133
This systematic review and individual patient data meta-analysis assesses the risks and benefits of ticagrelor monotherapy or clopidogrel monotherapy compared with standard dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI).
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JAMA
Original Investigation
August 9, 2022
Sigrid聽Sandner,聽MD; Bj枚rn聽Redfors,聽MD, PhD; Dominick J.听Angiolillo,聽MD; Katia聽Audisio,聽MD; Stephen E.听Fremes,聽MD; Paul W.A.听Janssen,聽MD; Alexander聽Kulik,聽MD; Roxana聽Mehran,聽MD; Joyce聽Peper,聽MD; Marc聽Ruel,聽MD; Jacqueline聽Saw,聽MD; Giovanni Jr聽Soletti,聽MD; Andrew聽Starovoytov,聽MD; Jurrien M.听ten Berg,聽MD; Laura M.听Willemsen,聽MD; Qiang聽Zhao,聽MD, PhD; Yunpeng聽Zhu,聽MD; Mario聽Gaudino,聽MD, PhD
free access
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JAMA. 2022; 328(6):554-562. 10.1001/jama.2022.11966
This systematic review and individual patient data meta-analysis of randomized clinical trials compares the effects of ticagrelor dual antiplatelet therapy or ticagrelor monotherapy with aspirin on saphenous vein graft failure among patients undergoing coronary artery bypass graft surgery.
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JAMA Cardiology
Review
June 1, 2022
Behnood聽Bikdeli,聽MD, MS; Farbod聽Zahedi Tajrishi,聽MD; Parham聽Sadeghipour,聽MD; Azita H.听Talasaz,聽PharmD; John聽Fanikos,聽RPH, MBA; Giuseppe聽Lippi,聽MD; Deborah M.听Siegal,聽MD, MSc; John W.听Eikelboom,聽MBBS; Manuel聽Monreal,聽MD, PhD; David聽Jimenez,聽MD, PhD; Jean M.听Connors,聽MD; Walter聽Ageno,聽MD, PhD; Geoffrey D.听Barnes,聽MD, MSc; Gregory聽Piazza,聽MD, MS; Dominick J.听Angiolillo,聽MD, PhD; Sahil A.听Parikh,聽MD; Ajay J.听Kirtane,聽MD, SM; Renato D.听Lopes,聽MD, PhD; Deepak L.听Bhatt,聽MD, MPH; Jeffrey I.听Weitz,聽MD; Roxana聽Mehran,聽MD; Harlan M.听Krumholz,聽MD, SM; Samuel Z.听Goldhaber,聽MD; Gregory Y. H.听Lip,聽MD
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JAMA Cardiol. 2022; 7(7):747-759. 10.1001/jamacardio.2022.1292
This narrative review evaluates the alignment between clinical practice and randomized clinical trial findings in the use of dose-reduced direct oral anticoagulants.
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JAMA Cardiology
Original Investigation
June 30, 2021
J. J.听Coughlan,聽MB, BCh; Alp聽Aytekin,聽MD; Shqipdona聽Lahu,聽MD; Gjin聽Ndrepepa,聽MD; Maurizio聽Menichelli,聽MD; Katharina聽Mayer,聽MD; Jochen聽W枚hrle,聽MD; Isabell聽Bernlochner,聽MD; Senta聽Gewalt,聽MD; Bernhard聽Witzenbichler,聽MD; Willibald聽Hochholzer,聽MD; Dirk聽Sibbing,聽MD; Salvatore聽Cassese,聽MD; Dominick J.听Angiolillo,聽MD, PhD; Rayyan聽Hemetsberger,聽MD; Christian聽Valina,聽MD; Arne聽M眉ller,聽MD; Sebastian聽Kufner,聽MD; Christoph聽Liebetrau,聽MD; Erion聽Xhepa,聽MD, PhD; Alexander聽Hapfelmeier,聽MSc; Hendrik B.听Sager,聽MD; Michael聽Joner,聽MD; Massimiliano聽Fusaro,聽MD; Gert聽Richardt,聽MD; Karl Ludwig聽Laugwitz,聽MD; Franz Josef聽Neumann,聽MD; Heribert聽Schunkert,聽MD; Stefanie聽Sch眉pke,聽MD; Adnan聽Kastrati,聽MD
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JAMA Cardiol. 2021; 6(10):1121-1129. 10.1001/jamacardio.2021.2228
This prespecified analysis of a randomized clinical trial assesses the safety and efficacy of ticagrelor vs prasugrel for patients with acute coronary syndrome (ACS) treated with percutaneous coronary intervention.
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JAMA Cardiology
Original Investigation
May 15, 2021
Birgit聽Vogel,聽MD; Usman聽Baber,聽MD, MS; David J.听Cohen,聽MD, MSc; Samantha聽Sartori,聽PhD; Samin K.听Sharma,聽MD; Dominick J.听Angiolillo,聽MD, PhD; Serdar聽Farhan,聽MD; Ridhima聽Goel,聽MD; Zhongjie聽Zhang,聽MPH; Carlo聽Briguori,聽MD, PhD; Timothy聽Collier,聽MSc; George聽Dangas,聽MD, PhD; Dariusz聽Dudek,聽MD, PhD; Javier聽Escaned,聽MD, PhD; Robert聽Gil,聽MD, PhD; Ya-ling聽Han,聽MD, PhD; Upendra聽Kaul,聽MD; Ran聽Kornowski,聽MD; Mitchell W.听Krucoff,聽MD; Vijay聽Kunadian,聽MBBS, MD; Shamir R.听Mehta,聽MD, MSc; David聽Moliterno,聽MD; E. Magnus聽Ohman,聽MD; Gennaro聽Sardella,聽MD; Bernhard聽Witzenbichler,聽MD; C. Michael聽Gibson,聽MD, MS; Stuart聽Pocock,聽PhD; Kurt聽Huber,聽MD; Roxana聽Mehran,聽MD
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JAMA Cardiol. 2021; 6(9):1032-1041. 10.1001/jamacardio.2021.1720
This subgroup analysis of a randomized clinical trial explores differences in outcomes by sex among patients treated with ticagrelor monotherapy vs ticagrelor plus aspirin after percutaneous coronary intervention.
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JAMA Internal Medicine
Research Letter
April 19, 2021
Irbaz聽Hameed,聽MD; N. U. Farrukh聽Hameed,聽MD, Mch; Christian T.听Oakley,聽BS; Ivancarmine聽Gambardella,聽MD; Claudio聽Bravo,聽MD; Dominick J.听Angiolillo,聽MD; Mario聽Gaudino,聽MD, MSCE, PhD
free access
JAMA Intern Med. 2021; 181(7):1003-1006. 10.1001/jamainternmed.2021.1051
This cross-sectional study examines the readability, accuracy, content, quality, and suitability of online health information on coronary artery bypass grafting or percutaneous coronary intervention for patients.
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JAMA Internal Medicine
Original Investigation
October 12, 2020
Mario聽Gaudino,聽MD, MSCE; Irbaz聽Hameed,聽MD; Michael E.听Farkouh,聽MD; Mohamed聽Rahouma,聽MD; Ajita聽Naik,聽MD; N. Bryce聽Robinson,聽MD; Yongle聽Ruan,聽MD; Michelle聽Demetres,聽MLIS; Giuseppe聽Biondi-Zoccai,聽MD, MStat; Dominick J.听Angiolillo,聽MD; Emilia聽Bagiella,聽MD; Mary E.听Charlson,聽MD; Umberto聽Benedetto,聽MD; Marc聽Ruel,聽MD; David P.听Taggart,聽MD; Leonard N.听Girardi,聽MD; Deepak L.听Bhatt,聽MD, MPH; Stephen E.听Fremes,聽MD
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JAMA Intern Med. 2020; 180(12):1638-1646. 10.1001/jamainternmed.2020.4748
This meta-analysis evaluates the difference in all-cause and cause-specific mortality in randomized clinical trials comparing percutaneous coronary intervention with coronary artery bypass grafting for the treatment of patients with coronary artery disease.
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JAMA Cardiology
Original Investigation
September 26, 2019
Mariusz聽Tomaniak,聽MD; Ply聽Chichareon,聽MD; Yoshinobu聽Onuma,聽MD, PhD; Efthymios N.听Deliargyris,聽MD; Kuniaki聽Takahashi,聽MD; Norihiro聽Kogame,聽MD; Rodrigo聽Modolo,聽MD; Chun Ching聽Chang,聽MD; Tessa聽Rademaker-Havinga,聽MSc; Robert F.听Storey,聽MD, DM; George D.听Dangas,聽MD, PhD; Deepak L.听Bhatt,聽MD, MPH; Dominick J.听Angiolillo,聽MD, PhD; Christian聽Hamm,聽MD, PhD; Marco聽Valgimigli,聽MD, PhD; Stephan聽Windecker,聽MD, PhD; Philippe Gabriel聽Steg,聽MD, PhD; Pascal聽Vranckx,聽MD, PhD; Patrick W.听Serruys,聽MD, PhD; for the GLOBAL LEADERS Trial Investigators
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JAMA Cardiol. 2019; 4(11):1092-1101. 10.1001/jamacardio.2019.3355
This secondary analysis of the GLOBAL LEADERS randomized clinical trial evaluates the benefit and risks of aspirin in addition to ticagrelor among patients with acute coronary syndrome beyond 1 month after percutaneous coronary intervention.
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JAMA
Original Contribution
January 18, 2012
Dominick J. Angiolillo, MD, PhD; Michael S. Firstenberg, MD; Matthew J. Price, MD; Pradyumna E. Tummala, MD; Martin Hutyra, MD; Ian J. Welsby, MD; Michele D. Voeltz, MD; Harish Chandna, MD; Chandrashekhar Ramaiah, MD; Miroslav Brtko, MD, PhD; Louis Cannon, MD; Cornelius Dyke, MD; Tiepu Liu, MD, PhD; Gilles Montalescot, MD; Steven V. Manoukian, MD; Jayne Prats, PhD; Eric J. Topol, MD; for the BRIDGE Investigators
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has multimedia
JAMA. 2012; 307(3):265-274. 10.1001/jama.2011.2002
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JAMA
Original Contribution
November 23, 2011
Jessica L. Mega, MD, MPH; Willibald Hochholzer, MD; Andrew L. Frelinger, PhD; Michael J. Kluk, MD, PhD; Dominick J. Angiolillo, MD; Dean J. Kereiakes, MD; Steven Isserman, MD; William J. Rogers, MD; Christian T. Ruff, MD, MPH; Charles Contant, PhD; Michael J. Pencina, PhD; Benjamin M. Scirica, MD, MPH; Janina A. Longtine, MD, PhD; Alan D. Michelson, MD; Marc S. Sabatine, MD, MPH
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JAMA. 2011; 306(20):2221-2228. 10.1001/jama.2011.1703
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JAMA
Editorial
September 21, 2011
Dominick J. Angiolillo, MD, PhD
JAMA. 2011; 306(11):1260-1261. 10.1001/jama.2011.1349
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JAMA
Original Contribution
March 16, 2011
Matthew J. Price, MD; Peter B. Berger, MD; Paul S. Teirstein, MD; Jean-Fran莽ois Tanguay, MD; Dominick J. Angiolillo, MD; Douglas Spriggs, MD; Sanjeev Puri, MD; Mark Robbins, MD; Kirk N. Garratt, MD; Olivier F. Bertrand, MD; Michael E. Stillabower, MD; Joseph R. Aragon, MD; David E. Kandzari, MD; Curtiss T. Stinis, MD; Michael S. Lee, MD; Steven V. Manoukian, MD; Christopher P. Cannon, MD; Nicholas J. Schork, PhD; Eric J. Topol, MD; for the GRAVITAS Investigators
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JAMA. 2011; 305(11):1097-1105. 10.1001/jama.2011.290