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  • JAMA Original Investigation
    April 6, 2024

    Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial

    Richard M.听Martin,聽BM, BS, PhD; Emma L.听Turner,聽PhD; Grace J.听Young,聽MSc; Chris聽Metcalfe,聽PhD; Eleanor I.听Walsh,聽MSc; J. Athene聽Lane,聽PhD; Jonathan A. C.听Sterne,聽PhD; Sian聽Noble,聽PhD; Peter聽Holding,聽MSc; Yoav聽Ben-Shlomo,聽MBBS, PhD; Naomi J.听Williams,聽PhD; Nora聽Pashayan,聽MD, PhD; Mai Ngoc聽Bui,聽PhD; Peter C.听Albertsen,聽MD; Tyler M.听Seibert,聽MD, PhD; Anthony L.听Zietman,聽MD; Jon聽Oxley,聽MD; Jan聽Adolfsson,聽MD; Malcolm D.听Mason,聽MD; George聽Davey Smith,聽DSc; David E.听Neal,聽MD; Freddie C.听Hamdy,聽MD; Jenny L.听Donovan,聽PhD; CAP Trial Group
    Abstract Full Text
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    JAMA. 2024; 331(17):1460-1470. 10.1001/jama.2024.4011

    This secondary analysis of a randomized clinical trial assesses whether screening for prostate-specific antigen reduces prostate cancer mortality at 15-year follow-up.

  • JAMA Original Investigation
    March 6, 2018

    Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial

    Richard M.听Martin,聽PhD; Jenny L.听Donovan,聽PhD; Emma L.听Turner,聽PhD; Chris聽Metcalfe,聽PhD; Grace J.听Young,聽MSc; Eleanor I.听Walsh,聽MSc; J. Athene聽Lane,聽PhD; Sian聽Noble,聽PhD; Steven E.听Oliver,聽PhD; Simon聽Evans,聽MD; Jonathan A. C.听Sterne,聽PhD; Peter聽Holding,聽MSc; Yoav聽Ben-Shlomo,聽PhD; Peter聽Brindle,聽MD; Naomi J.听Williams,聽PhD; Elizabeth M.听Hill,聽MSc; Siaw Yein聽Ng,聽PhD; Jessica聽Toole,聽MSc; Marta K.听Tazewell,聽MSc; Laura J.听Hughes,聽BA; Charlotte F.听Davies,聽PhD; Joanna C.听Thorn,聽PhD; Elizabeth聽Down,聽MSc; George聽Davey Smith,聽DSc; David E.听Neal,聽MD; Freddie C.听Hamdy,聽MD; CAP Trial Group
    Abstract Full Text
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    JAMA. 2018; 319(9):883-895. 10.1001/jama.2018.0154

    This cluster randomized trial evaluates the effect of a single prostate-specific antigen (PSA) screening test on 10-year prostate cancer鈥搒pecific mortality among men aged 50 to 69 years treated at UK primary care practices.

  • JAMA Original Investigation
    August 22, 2017

    Effect of Oral Prednisolone on Symptom Duration and Severity in Nonasthmatic Adults With Acute Lower Respiratory Tract Infection: A Randomized Clinical Trial

    Alastair D.听Hay,聽FRCGP; Paul聽Little,聽FMedSci; Anthony聽Harnden,聽FRCGP; Matthew聽Thompson,聽PhD; Kay聽Wang,聽DPhil; Denise聽Kendrick,聽FRCGP; Elizabeth聽Orton,聽FFPH; Sara T.听Brookes,聽PhD; Grace J.听Young,聽MSc; Margaret聽May,聽PhD; Sandra聽Hollinghurst,聽PhD; Fran E.听Carroll,聽PhD; Harriet聽Downing,聽MPhil; David聽Timmins,聽BA; Natasher聽Lafond,聽MSc; Magdy聽El-Gohary,聽MRCGP; Michael聽Moore,聽FRCGP
    Abstract Full Text
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    JAMA. 2017; 318(8):721-730. 10.1001/jama.2017.10572

    This randomized trial compares the effect of prednisolone vs placebo on duration of moderately bad or worse cough and severity of symptoms in nonasthmatic adults with acute lower respiratory infections.