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This randomized clinical trial evaluates clopidogrel monotherapy vs dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions who are at high bleeding and ischemic risk.

This secondary analysis of a randomized clinical trial assesses the association of aspirin, clopidogrel, and their combination with gastrointestinal injury progression among patients in China without high bleeding risk after percutaneous coronary intervention.

This study assesses process of care and health outcomes in people identified as minimal risk for coronary artery disease when testing is deferred.

This randomized clinical trial investigates the optimal initial evaluation pathway to reduce unnecessary testing referral for patients with suspected coronary artery disease who are symptomatic but in stable condition.

This pooled analysis includes data from 4 major randomized clinical trials that compare PCI with drug-eluting stents vs CABG to assess differences in outcomes for patients with left main coronary artery disease with and without acute coronary syndrome.

This secondary analysis of a randomized clinical trial evaluates clinical and quality-of-life outcomes following invasive and conservative management of chronic kidney disease.

This secondary analysis of the COAPT randomized clinical trial explores the contributions of the degree of secondary mitral regurgitation using the effective regurgitation orifice area, regurgitant volume, and left ventricular end-diastolic volume index to the benefit of transcatheter mitral valve repair.

This cross-sectional study assesses the prevalence of multiplicity and whether appropriate multiplicity adjustments were performed among cardiovascular randomized clinical trials published in 6 medical journals with a high impact factor.

This individual patient data pooled analysis and meta-analysis examines the outcomes of first-generation bioresorbable vascular scaffolds in patients with coronary artery disease before and after 3 years.

This cross-sectional multiple-center study adapts an anatomical scoring system for use with registry data, allowing facile and automatic calculation of scores and association with clinical outcomes among patients undergoing percutaneous or surgical revascularization.

This Viewpoint discusses the relative outcomes of percutaneous coronary intervention and coronary artery bypass grafting, specifically with regards to patient-centered decision making.

This analysis of data from the International Study of Comparative Health Effectiveness With Medical and Invasive Approaches trial (ISCHEMIA) tdescribes baseline characteristics of participants enrolled and randomized in the trial and evaluates whether qualification by stress imaging or nonimaging exercise tolerance test influenced risk profiles.

This pooled-analysis investigates the long-term safety and efficacy of new-generation drug-eluting stents vs early-generation drug-eluting stents in women with acute myocardial infarction.

This secondary analysis of a randomized clinical trial assesses whether a link exists between the length of procedure time and acute stent thrombosis in patients treated with bivalirudin vs heparin plus glycoprotein IIb/IIIa inhibitor.

This exploratory analysis of the 3 CHAMPION trials evaluates the use of cangrelor with glycoprotein IIb/IIIa inhibitors compared with cangrelor alone in patients undergoing percutaneous coronary intervention.

This narrative review examines the associations of coronary artery stenosis, plaque morphology, and fractional flow reserve and the prognostic value of fractional flow reserve.

This randomized superiority trial in China found that among patients undergoing PCI, bivalirudin was associated with reduced adverse effects compared with heparin alone and heparin plus tirofiban.