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  • Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial

    Abstract Full Text
    ÁñÁ«ÊÓƵ Neurol. 2023; 80(8):779-788. 10.1001/jamaneurol.2023.1660

    This randomized clinical trial investigates the safety and efficacy of ApTOLL as a neuroprotectant drug for patients with ischemic stroke when given in combination with endovascular treatment.

  • Noncontrast Computed Tomography vs Computed Tomography Perfusion or Magnetic Resonance Imaging Selection in Late Presentation of Stroke With Large-Vessel Occlusion

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    ÁñÁ«ÊÓƵ Neurol. 2021; 79(1):22-31. 10.1001/jamaneurol.2021.4082

    This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.

  • Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone

    Abstract Full Text
    free access
    ÁñÁ«ÊÓƵ Neurol. 2021; 78(3):321-328. 10.1001/jamaneurol.2020.4557

    This cohort study aims to develop and validate an easily applicable predictive score of early neurological deterioration of presumed ischemic origin following intravenous thrombolysis in patients with minor stroke and large vessel occlusion (LVO).

  • Poststroke Dementia: Influence of Hippocampal Atrophy

    Abstract Full Text
    free access
    Arch Neurol. 2003; 60(4):585-590. 10.1001/archneur.60.4.585