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  • Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial

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    JAMA. 2024; 331(17):1460-1470. 10.1001/jama.2024.4011

    This secondary analysis of a randomized clinical trial assesses whether screening for prostate-specific antigen reduces prostate cancer mortality at 15-year follow-up.

  • Comparison of Multiparametric Magnetic Resonance Imaging and Targeted Biopsy With Systematic Biopsy Alone for the Diagnosis of Prostate Cancer: A Systematic Review and Meta-analysis

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    open access
    ÁñÁ«ÊÓƵ Netw Open. 2019; 2(8):e198427. 10.1001/jamanetworkopen.2019.8427

    This systematic review and meta-analysis investigates whether magnetic resonance imaging combined with targeted biopsy is associated with improved detection of clinically significant prostate cancer compared with transrectal ultrasonography–guided systematic prostate biopsy alone.

  • Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial

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    free access
    JAMA. 2018; 319(9):883-895. 10.1001/jama.2018.0154

    This cluster randomized trial evaluates the effect of a single prostate-specific antigen (PSA) screening test on 10-year prostate cancer–specific mortality among men aged 50 to 69 years treated at UK primary care practices.

  • Patient-Reported Outcomes Following Treatment for Localized Prostate Cancer: Helping Decision Making for Patients and Their Physicians

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    JAMA. 2017; 317(11):1121-1123. 10.1001/jama.2017.1703