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This randomized clinical trial evaluates clopidogrel monotherapy vs dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions who are at high bleeding and ischemic risk.

This randomized clinical trial assesses the efficacy of Tongxinluo, a traditional Chinese medicine compound, vs placebo in improving clinical outcomes in patients with ST-segment elevation myocardial infarction.

This randomized clinical trial compares the improvement in clinical outcomes following the administration of topotecan alone with that of berzosertib plus topotecan among patients with relapsed small cell lung cancer.

This cohort study evaluates the role of artificial intelligence in the association between time of day and colonoscopy quality.

This cohort study analyzes whether children’s screen time exposure between ages 6 and 72 months is associated with their cognitive and social-emotional development.

This cohort study assesses the safety and medium-term outcomes of percutaneous intramyocardial septal radiofrequency ablation in a large patient cohort with drug-refractory hypertrophic obstructive cardiomyopathy.

This cross-sectional study evaluates anti–SARS-CoV-2 spike protein receptor binding domain and neutralizing antibody responses to COVID-19 vaccines longitudinally over 6 months in patients with cancer undergoing treatment or who received a stem cell transplant.

This cohort study uses Danish national registry data to assess the association of maternal autoimmune diseases before childbirth with risk of mental disorders among offspring up to early adulthood.

This cohort study using long-term follow-up data from a clinical trial examines outcomes associated with adding transcatheter arterial chemoembolization to radiofrequency ablation for treatment of early hepatocellular carcinoma.

This cohort study uses pretreatment computed tomography (CT)–pixelated feature-difference extraction techniques to identify diagnostically relevant features that could predict patients’ response to neoadjuvant chemotherapy for locally advanced gastric cancer.

This cross-sectional study compared preeclampsia prevalence, risk factors, and pregnancy outcomes between the Swedish and Chinese populations.

This cross-sectional study examines the variations in care and outcomes of patients with acute ST-segment elevation myocardial infarction (STEMI) at 3 different levels of hospitals—province, prefecture, and county—in China.

This cohort study estimates the associations between grandparental age at the time their children were born and the risk of autism spectrum disorders in their grandchildren.

This cohort study assesses the procedural success and major adverse event rates associated with left atrial appendage occlusion procedures among patients in China.

This cohort study investigates the extent to which post–percutaneous coronary intervention (PCI) fractional flow reserve (FFR) mediates the association of pre-PCI FFR with vessel-related outcomes using an international, multicenter collaboration registry.

This randomized clinical trial compares the effects of moderate and vigorous exercise on intrahepatic triglyceride content and metabolic risk factors among patients with nonalcoholic fatty liver disease.