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  • Extended Clopidogrel Monotherapy vs DAPT in Patients With Acute Coronary Syndromes at High Ischemic and Bleeding Risk: The OPT-BIRISK Randomized Clinical Trial

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    JAMA Cardiol. 2024; 10.1001/jamacardio.2024.0534

    This randomized clinical trial evaluates clopidogrel monotherapy vs dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions who are at high bleeding and ischemic risk.

  • Automated Electronic Alert for the Care and Outcomes of Adults With Acute Kidney Injury: A Randomized Clinical Trial

    Abstract Full Text
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    ÁñÁ«ÊÓƵ Netw Open. 2024; 7(1):e2351710. 10.1001/jamanetworkopen.2023.51710

    This randomized clinical trial evaluates the implementation of an automated warning system and its effect on the management and outcomes of acute kidney injury (AKI).

  • USPSTF Recommendation on Screening for Lipid Disorders in Children and Adolescents—Reply

    Abstract Full Text
    JAMA. 2023; 330(20):2024-2025. 10.1001/jama.2023.20452
  • Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis: The EXIT-SEP Randomized Clinical Trial

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    JAMA Intern Med. 2023; 183(7):647-655. 10.1001/jamainternmed.2023.0780

    This randomized clinical trial assesses the effect of Xuebijing injection vs placebo on 28-day mortality among patients with sepsis.

  • Characterization of Premigration and Postmigration Multidomain Factors and Psychosocial Health Among Refugee Children and Adolescents After Resettlement in Australia

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    ÁñÁ«ÊÓƵ Netw Open. 2023; 6(4):e235841. 10.1001/jamanetworkopen.2023.5841

    This cross-sectional study estimates the associations of premigration and postmigration multidomain factors with psychosocial health after resettlement among refugee children and adolescents in the Building a New Life in Australia cohort.

  • Efficacy and Safety of Esketamine for Supplemental Analgesia During Elective Cesarean Delivery: A Randomized Clinical Trial

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    ÁñÁ«ÊÓƵ Netw Open. 2023; 6(4):e239321. 10.1001/jamanetworkopen.2023.9321

    This randomized clinical trial investigates the sedative and analgesic effects of intravenous esketamine used before childbirth via cesarean delivery with epidural anesthesia in women in China.

  • Acupuncture for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Randomized Clinical Trial

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    ÁñÁ«ÊÓƵ Netw Open. 2022; 5(12):e2248817. 10.1001/jamanetworkopen.2022.48817

    This pilot randomized clinical trial of patients with irritable bowel syndrome with diarrhea examines whether the use of US Food and Drug Administration–recommended end points is feasible for determining the efficacy of acupuncture.

  • Doxycycline vs Placebo at 12 Weeks in Patients With Mild Thyroid-Associated Ophthalmopathy: A Randomized Clinical Trial

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    JAMA Ophthalmol. 2022; 140(11):1076-1083. 10.1001/jamaophthalmol.2022.3779

    This randomized clinical trial evaluates the efficacy of doxycycline vs placebo in patients with mild thyroid-associated ophthalmopathy.

  • Two-Year Health Outcomes in Hospitalized COVID-19 Survivors in China

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    ÁñÁ«ÊÓƵ Netw Open. 2022; 5(9):e2231790. 10.1001/jamanetworkopen.2022.31790

    This cohort study assesses the health outcomes among hospitalized COVID-19 survivors over 2 years to identify factors associated with increased risk of persistent symptoms.

  • Concordance of SARS-CoV-2 Results in Self-collected Nasal Swabs vs Swabs Collected by Health Care Workers in Children and Adolescents

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    JAMA. 2022; 328(10):935-940. 10.1001/jama.2022.14877

    This cross-sectional study examines the ability of school-aged children, aged 4 to 14 years, to self-collect nasal swabs for SARS-CoV-2 testing after hearing and seeing simple instructions compared with collection by health care workers.

  • Anti-Asian Hate and the Health of Older Asian Individuals

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    JAMA Intern Med. 2024; 10.1001/jamainternmed.2024.1090

    This qualitative study assesses the association of anti-Asian hate with older Asian individuals’ health and the clinician’s role in addressing hate incidents.

  • Effect of Apatinib Plus Pegylated Liposomal Doxorubicin vs Pegylated Liposomal Doxorubicin Alone on Platinum-Resistant Recurrent Ovarian Cancer: The APPROVE Randomized Clinical Trial

    Abstract Full Text
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    JAMA Oncol. 2022; 8(8):1169-1176. 10.1001/jamaoncol.2022.2253

    This randomized clinical trial examines the efficacy and safety of treatment with apatinib plus pegylated liposomal doxorubicin in Chinese patients with platinum-resistant recurrent ovarian cancer.

  • Endovascular Therapy and Outcomes Among Patients With Very Large Ischemic Core Stroke

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    ÁñÁ«ÊÓƵ Netw Open. 2024; 7(5):e249298. 10.1001/jamanetworkopen.2024.9298

    This cohort study explores outcomes associated with endovascular therapy vs standard medical treatment alone for patients with very large ischemic core stroke, as assessed with noncontrast computed tomography.

  • Laparoscopic Spleen-Preserving Hilar Lymphadenectomy for Advanced Proximal Gastric Cancer Without Greater Curvature Invasion: Five-Year Outcomes From the Fuges-02 Randomized Clinical Trial

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    JAMA Surg. 2024; 10.1001/jamasurg.2024.1023

    This secondary analysis of a randomized clinical trial examines 5-year outcomes of laparoscopic total gastrectomy with laparoscopic spleen-preserving splenic hilar lymphadenectomy vs laparoscopic total gastrectomy for resectable advanced proximal gastric cancer without greater curvature invasion.

  • Perceived Economic Burden, Mortality, and Health Status in Patients With Heart Failure

    Abstract Full Text
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    ÁñÁ«ÊÓƵ Netw Open. 2024; 7(3):e241420. 10.1001/jamanetworkopen.2024.1420

    This cohort study investigates whether perceived economic burden is associated with all-cause mortality and rehospitalization for heart failure among patients with acute decompensated heart failure.

  • One-Year Trajectory of Cognitive Changes in Older Survivors of COVID-19 in Wuhan, China: A Longitudinal Cohort Study

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    ÁñÁ«ÊÓƵ Neurol. 2022; 79(5):509-517. 10.1001/jamaneurol.2022.0461

    This cohort study evaluates cognitive functioning and decline in elderly COVID-19 survivors in China over a period of 12 months postinfection.

  • Physical Fitness and Risk of Mental Disorders in Children and Adolescents

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    JAMA Pediatr. 2024; 10.1001/jamapediatrics.2024.0806

    This cohort study evaluates the association between physical fitness and mental disorder risks in children and adolescents in Taiwan.

  • Effect of Dexmedetomidine on Postpartum Depression in Women With Prenatal Depression: A Randomized Clinical Trial

    Abstract Full Text
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    ÁñÁ«ÊÓƵ Netw Open. 2024; 7(1):e2353252. 10.1001/jamanetworkopen.2023.53252

    This randomized clinical trial assesses the efficacy and safety of dexmedetomidine for prevention of postpartum depression among women with prenatal depression undergoing cesarean delivery.

  • Urban Living Environment and Myopia in Children

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    ÁñÁ«ÊÓƵ Netw Open. 2023; 6(12):e2346999. 10.1001/jamanetworkopen.2023.46999

    This cohort study evaluates the association of urbanization with risk of myopia and myopia progression and with myopia severity in elementary school students.

  • ADHD Pharmacotherapy and Mortality in Individuals With ADHD

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    JAMA. 2024; 331(10):850-860. 10.1001/jama.2024.0851

    This cohort study investigates whether the initiation of medication to treat patients with attention-deficit/hyperactivity disorder (ADHD) was associated with mortality.