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This randomized clinical trial evaluates clopidogrel monotherapy vs dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions who are at high bleeding and ischemic risk.

This meta-analysis compares the efficacy and safety of neoadjuvant-adjuvant anti–programmed cell death 1 (PD-1) and anti–programmed death ligand 1 (PD-L1) therapy with neoadjuvant-only anti–PD-1 and anti–PD-L1 therapy for patients with resectable non–small cell lung cancer (NSCLC).

This cross-sectional study evaluates hospital variation in cesarean rates in China in 2020 for term, singleton, live, vertex deliveries among women with no prior cesarean delivery.

This study investigates the 4-year progression of myopic maculopathy in children and adolescents with high myopia and explores potential risk factors.

This genome-wide pleiotropic association study sequentially investigates the pleiotropic associations from genetic and biological pathways to disentangle the underlying shared genetic etiology between 4 gastrointestinal tract diseases and 6 psychiatric disorders.

This study attempts to assess global ocular deformation in pathologic myopia.

This multicenter cohort study assesses whether serial postsurgical and postchemotherapy analyses of circulating tumor DNA levels could provide a real-time indication of adjuvant therapy efficacy in patients with stage III colon cancer.

This randomized clinical trial determines if swab pressing is noninferior to stromal hydration in sealing incisions and compares the efficacy of both techniques in preventing transient collapse of the anterior chamber in phacoemulsification for age-related cataract.

This study examines the prognostic utility and advantages of ctDNA analysis in all 3 stages of nonmetastatic colorectal cancer.

This randomized clinical trial examines the efficacy and toxic effects of postoperative capecitabine vs oxaliplatin plus capecitabine with radiotherapy for stage II and III rectal cancer.

This meta-analysis models the time course of placebo response in patients receiving oral treatment for osteoarthritis.

This cohort study uses data from the Taiwan National Health Insurance Research Database to assess whether prenatal benzodiazepine exposure was associated with development of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD).

This prognostic study establishes and validates a model based on vessels encapsulating tumor clusters and microvascular invasion to estimate recurrence-free survival in patients undergoing radical hepatectomy for hepatocellular carcinoma.

This randomized clinical trial compares the incidence of incision-related Descemet membrane detachment between eyes undergoing modified vs conventional 2.2-mm incision phacoemulsification for hard nuclear age-related cataract.

This cohort study assesses whether longitudinal patterns of habitual sleep duration are associated with subsequent risk of cardiovascular events and all-cause mortality in adults enrolled in a population-based study in China.

This genetic association study investigates the genetics of depression across multiple data sets of individuals of East Asian and European descent living in different countries and within different nongenetic cultural contexts.

This randomized clinical trial compares the effect of a balanced solution vs saline solution on 90-day survival in critically ill patients.

This systematic review and meta-analysis identifies the global prevalence and incidence of oral lichen planus in the overall population and among subgroups.