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Ƶ Neurology
Original Investigation
January 2, 2024
Raul G.Nogueira,Ѷ; Donald Lobsien,Ѷ; Joachim Klisch,Ѷ; Daniel Pielenz,Ѷ; Elmar Lobsien,Ѷ; Eric Sauvageau,Ѷ; Nima Aghaebrahim,Ѷ; Markus Möhlenbruch,Ѷ; Dominik Vollherbst,Ѷ; Christian Ulfert,Ѷ; Hormozd Bozorgchami,Ѷ; Wayne Clark,Ѷ; Ryan Priest,Ѷ; Edgar A.Samaniego,Ѷ; Santiago Ortega-Gutierrez,Ѷ, MSc; Malik Ghannam,Ѷ; Demetrius Lopes,Ѷ; Joshua Billingsley,Ѷ; Kiffon Keigher, DNP, ACNP; Diogo C.Haussen,Ѷ; Alhamza R.Al-Bayati,Ѷ; Adnan Siddiqui,Ѷ, PhD; Elad Levy,Ѷ, MBA; Michael Chen,Ѷ; Stephan Munich,Ѷ; Peter Schramm,Ѷ; Tobias Boppel,Ѷ; Sandra Narayanan,Ѷ; Bradley A.Gross,Ѷ; Christian Roth,Ѷ; Tobias Boeckh-Behrens,Ѷ; Ameer Hassan, DO; Johanna Fifi,Ѷ; Ron F.Budzik,Ѷ; Jason Tarpley,Ѷ; Robert M.Starke,Ѷ; Eytan Raz,Ѷ; Gary Brogan, MSc, BSc; David S.Liebeskind,Ѷ; Ricardo A.Hanel,Ѷ, PhD
open access
Ƶ Neurol. 2024; 81(2):170-178. 10.1001/jamaneurol.2023.5010
This randomized clinical trial evaluates whether thrombectomy for large vessel occlusion stroke with the pRESET stent retriever is noninferior to treatment with the Solitaire stent retriever.
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Ƶ Network Open
Original Investigation
Neurology
October 24, 2022
Hamidreza Saber,Ѷ; Shashvat M.Desai,Ѷ; Diogo Haussen,Ѷ; Alhamza Al-bayati,Ѷ; Shahram Majidi,Ѷ; J.Mocco,Ѷ; Ameer E.Hassan,Ѷ; Gary Rajah,Ѷ; Muhammad Waqas,Ѷ; Jason M.Davies,Ѷ; David Dornbos III,Ѷ; Christopher Nickele,Ѷ; Adam S.Arthur,Ѷ; Ashkan Mowla,Ѷ; Matthew S.Tenser,Ѷ; Maxim Mokin,Ѷ; Elliot Pressman,Ѷ; Amin Aghaebrahim,Ѷ; Ricardo A.Hanel,Ѷ; Santiago Ortega-Gutierrez,Ѷ, MSc; Tudor Jovin,Ѷ; Gary R.Duckwiler,Ѷ; David S.Liebeskind,Ѷ; Raul G.Nogueira,Ѷ; Jeffrey Gornbein, DrPH; Jeffrey L.Saver,Ѷ; Ashutosh P.Jadhav,Ѷ, PHD
open access
Ƶ Netw Open. 2022; 5(10):e2238154. 10.1001/jamanetworkopen.2022.38154
This cohort study compares the safety and efficacy outcomes associated with endovascular therapy vs medical management alone in the treatment of distal, medium vessel occlusion.
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Ƶ Neurology
Comment & Response
February 14, 2022
Gregory W.Albers,Ѷ; Scott Brown, PhD; Raul G.Nogueira,Ѷ
Ƶ Neurol. 2022; 79(4):418-419. 10.1001/jamaneurol.2021.5405
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Ƶ Neurology
Original Investigation
November 8, 2021
Thanh N.Nguyen,Ѷ; Mohamad Abdalkader,Ѷ; Simon Nagel,Ѷ; Muhammad M.Qureshi, MPH; Marc Ribo,Ѷ, PhD; Francois Caparros,Ѷ; Diogo C.Haussen,Ѷ; Mahmoud H.Mohammaden,Ѷ, MSc; Sunil A.Sheth,Ѷ; Santiago Ortega-Gutierrez,Ѷ, MSc; James E.Siegler,Ѷ; Syed Zaidi,Ѷ; Marta Olive-Gadea,Ѷ; Hilde Henon,Ѷ, PhD; Markus A.Möhlenbruch,Ѷ; Alicia C.Castonguay, PhD; Stefania Nannoni,Ѷ; Johannes Kaesmacher,Ѷ; Ajit S.Puri,Ѷ; Fatih Seker,Ѷ; Mudassir Farooqui,Ѷ, MPH; Sergio Salazar-Marioni,Ѷ; Anna L.Kuhn,Ѷ; Artem Kaliaev,Ѷ; Behzad Farzin,Ѷ; William Boisseau,Ѷ; Hesham E.Masoud,Ѷ; Carlos Ynigo Lopez,Ѷ; Ameena Rana,Ѷ; Samer Abdul Kareem,Ѷ; Anvitha Sathya; Piers Klein; Mohammad W.Kassem,Ѷ, MBA; Peter A.Ringleb,Ѷ; Charlotte Cordonnier,Ѷ, PhD; Jan Gralla,Ѷ; Urs Fischer,Ѷ, MSc; Patrik Michel,Ѷ; Tudor G.Jovin,Ѷ; Jean Raymond,Ѷ; Osama O.Zaidat,Ѷ, MS; Raul G.Nogueira,Ѷ
open access
is active quiz
Ƶ Neurol. 2021; 79(1):22-31. 10.1001/jamaneurol.2021.4082
This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.
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Ƶ Network Open
Original Investigation
Neurology
November 5, 2021
Aravind Ganesh,Ѷ, DPhil; Johanna M.Ospel,Ѷ; Bijoy K.Menon,Ѷ, MSc; Andrew M.Demchuk,Ѷ; Ryan A.McTaggart,Ѷ; Raul G.Nogueira,Ѷ; Alexandre Y.Poppe,Ѷ, CM; Mohammed A.Almekhlafi,Ѷ, MSc; Ricardo A.Hanel,Ѷ, PhD; Götz Thomalla,Ѷ; Staffan Holmin,Ѷ; Volker Puetz,Ѷ; Brian A.van Adel,Ѷ; Jason W.Tarpley,Ѷ; Michael Tymianski,Ѷ, PhD; Michael D.Hill,Ѷ, MSc; Mayank Goyal,Ѷ, PhD; ESCAPE-NA1 Trial Investigators
open access
Ƶ Netw Open. 2021; 4(11):e2132376. 10.1001/jamanetworkopen.2021.32376
This cohort study validates exploratory findings from the Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion with Emphasis on Minimizing CT to Recanalization Times (ESCAPE) trial regarding pretreatment, treatment, and posttreatment factors associated with discrepancies between follow-up infarct volume and 90-day functional outcome.
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Ƶ Neurology
Original Investigation
July 26, 2021
Gregory W.Albers,Ѷ; Maarten G.Lansberg,Ѷ, PhD; Scott Brown, PhD; Ashutosh P.Jadhav,Ѷ, PhD; Diogo C.Haussen,Ѷ; Sheila O.Martins,Ѷ, PhD; Leticia C.Rebello,Ѷ; Andrew M.Demchuk,Ѷ; Mayank Goyal,Ѷ, PhD; Marc Ribo,Ѷ; Aquilla S.Turk, DO; David S.Liebeskind,Ѷ; Jeremy J.Heit,Ѷ, PhD; Michael P.Marks,Ѷ; Tudor G.Jovin,Ѷ; Raul G.Nogueira,Ѷ; AURORA Investigators
free access
Ƶ Neurol. 2021; 78(9):1064-1071. 10.1001/jamaneurol.2021.2319
This pooled analysis uses data from 6 randomized clinical trials to assess the potential benefits of endovascular thrombectomy among patients with ischemic stroke based on 3 baseline imaging profiles.
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JAMA
Original Investigation
January 19, 2021
Wenjie Zi,Ѷ; Zhongming Qiu,Ѷ; Fengli Li,Ѷ; Hongfei Sang,Ѷ; Deping Wu,Ѷ; Weidong Luo,Ѷ; Shuai Liu,Ѷ; Junjie Yuan,Ѷ; Jiaxing Song,Ѷ; Zhonghua Shi,Ѷ; Wenguo Huang,Ѷ; Min Zhang, MS; Wenhua Liu,Ѷ; Zhangbao Guo, MS; Tao Qiu,Ѷ; Qiang Shi, MS; Peiyang Zhou,Ѷ; Li Wang,Ѷ; Xinmin Fu,Ѷ; Shudong Liu,Ѷ; Shiquan Yang,Ѷ; Shuai Zhang,Ѷ; Zhiming Zhou,Ѷ; Xianjun Huang,Ѷ; Yan Wang,Ѷ; Jun Luo, MS; Yongjie Bai,Ѷ; Min Zhang, MS; Youlin Wu, MS; Guoyong Zeng,Ѷ; Yue Wan,Ѷ; Changming Wen,Ѷ; Hongbin Wen,Ѷ; Wentong Ling, MS; Zhuo Chen, MS; Miao Peng, MS; Zhibing Ai,Ѷ; Fuqiang Guo,Ѷ; Huagang Li,Ѷ; Jing Guo, MS; Haitao Guan,Ѷ; Zhiyi Wang, MS; Yong Liu, MS; Jie Pu,Ѷ; Zhen Wang,Ѷ; Hansheng Liu,Ѷ; Luming Chen,Ѷ; Jiacheng Huang,Ѷ; Guoqiang Yang,Ѷ; Zili Gong,Ѷ; Jie Shuai,Ѷ; Raul G.Nogueira,Ѷ; Qingwu Yang,Ѷ, PhD; DEVT Trial Investigators
free access
has multimedia
JAMA. 2021; 325(3):234-243. 10.1001/jama.2020.23523
This noninferiority trial compares the effects of endovascular treatment with vs without intravenous alteplase on 90-day functional independence among patients with acute ischemic stroke.
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Ƶ Neurology
Comment & Response
May 4, 2020
Simon Nagel,Ѷ; Diogo C.Haussen,Ѷ; Raul G.Nogueira,Ѷ
Ƶ Neurol. 2020; 77(7):905-906. 10.1001/jamaneurol.2020.0848
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Ƶ Neurology
Original Investigation
January 7, 2019
Anna M. M.Boers, PhD; Ivo G. H.Jansen,Ѷ, PhD; Scott Brown, PhD; Hester F.Lingsma, PhD; Ludo F. M.Beenen,Ѷ; Thomas G.Devlin,Ѷ, PhD; Luis San Román,Ѷ, PhD; Ji-Hoe Heo,Ѷ, PhD; Marc Ribó,Ѷ; Mohammed A.Almekhlafi,Ѷ, FRCPC; David S.Liebeskind,Ѷ; Jeanne Teitelbaum,Ѷ; Patricia Cuadras,Ѷ; Richard du Mesnil de Rochemont,Ѷ, PhD; Marine Beaumont, PhD; Martin M.Brown,Ѷ, FRCP; Albert J.Yoo,Ѷ, PhD; Geoffrey A.Donnan,Ѷ; Jean Louis Mas,Ѷ; Catherine Oppenheim, PhD; Richard J.Dowling, MBBS; Thierry Moulin,Ѷ, PhD; Nelly Agrinier,Ѷ, PhD; Demetrius K.Lopes,Ѷ; Lucía Aja Rodríguez,Ѷ; Kars C. J.Compagne, MSc; Fahad S.Al-Ajlan,Ѷ; Jeremy Madigan, MB ChB; Gregory W.Albers,Ѷ; Sebastien Soize,Ѷ; Jordi Blasco,Ѷ, PhD; Stephen M.Davis,Ѷ; Raul G.Nogueira,Ѷ; Antoni Dávalos,Ѷ, PhD; Bijoy K.Menon,Ѷ; Aad van der Lugt,Ѷ, PhD; Keith W.Muir,Ѷ; Yvo B. W. E. M.Roos,Ѷ, PhD; Phil White,Ѷ, PhD; Peter J.Mitchell,Ѷ; Andrew M.Demchuk,Ѷ, FRCPC; Wim H.van Zwam,Ѷ; Tudor G.Jovin,Ѷ; Robert J.van Oostenbrugge,Ѷ, PhD; Diederik W. J.Dippel,Ѷ, PhD; Bruce C. V.Campbell, PhD, FRACP; Francis Guillemin,Ѷ, PhD; Serge Bracard, PhD; Michael D.Hill,Ѷ; Mayank Goyal,Ѷ, FRCPC; Henk A.Marquering, PhD; Charles B. L. M.Majoie,Ѷ, PhD
free access
Ƶ Neurol. 2019; 76(2):194-202. 10.1001/jamaneurol.2018.3661
This pooled data analysis of 7 randomized clinical trials of thrombectomy for acute ischemic stroke examines whether follow-up infarct volume mediates the relationship between endovascular therapy and functional outcome in patients with acute ischemic stroke.
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Ƶ Neurology
Review
November 5, 2018
Song J.Kim,Ѷ; Raul G.Nogueira,Ѷ; Diogo C.Haussen,Ѷ
Ƶ Neurol. 2018; 76(3):355-361. 10.1001/jamaneurol.2018.3366
This narrative review addresses the current understanding of carotid webs as a modifiable risk factor for stroke.
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Ƶ Neurology
Original Investigation
March 1, 2018
Raul G.Nogueira,Ѷ; Donald Frei,Ѷ; Jawad F.Kirmani,Ѷ; Osama Zaidat,Ѷ; Demetrius Lopes,Ѷ; Aquilla S.Turk III,Ѷ; Donald Heck,Ѷ; Brian Mason,Ѷ; Diogo C.Haussen,Ѷ; Elad I.Levy,Ѷ; Siddhart Mehta,Ѷ; Marc Lazzaro,Ѷ; Michael Chen,Ѷ; Arnd Dörfler,Ѷ; Albert J.Yoo,Ѷ; Colin P.Derdeyn,Ѷ; Lee Schwamm,Ѷ; David Langer,Ѷ; Adnan Siddiqui,Ѷ, PhD; for the Penumbra Separator 3D Investigators
free access
Ƶ Neurol. 2018; 75(3):304-311. 10.1001/jamaneurol.2017.3967
This randomized clinical noninferiority trial assesses a novel 3-dimensional stent retriever when used in conjunction with aspiration-based mechanical thrombectomy compared with aspiration-based mechanical thrombectomy alone in patients with acute ischemic stroke.
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Ƶ Neurology
Original Investigation
June 1, 2017
Ashutosh P.Jadhav,Ѷ, PhD; Mehdi Bouslama,Ѷ; Amin Aghaebrahim,Ѷ; Leticia C.Rebello,Ѷ; Matthew T.Starr,Ѷ; Diogo C.Haussen,Ѷ; Manasa Ranginani, MBBS; Matthew K.Whalin,Ѷ, PhD; Tudor G.Jovin,Ѷ; Raul G.Nogueira,Ѷ
free access
Ƶ Neurol. 2017; 74(6):704-709. 10.1001/jamaneurol.2017.0192
This case-control study compares clinical and angiographic outcomes between monitored anesthesia care and general anesthesia in patients presenting with vertebrobasilar occlusion strokes.
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Ƶ Neurology
Original Investigation
March 1, 2017
Jonathan M.Coutinho,Ѷ; David S.Liebeskind,Ѷ; Lee-Anne Slater,Ѷ; Raul G.Nogueira,Ѷ; Wayne Clark,Ѷ; Antoni Dávalos,Ѷ; Alain Bonafé,Ѷ; Reza Jahan,Ѷ; Urs Fischer,Ѷ; Jan Gralla,Ѷ; Jeffrey L.Saver,Ѷ; Vitor M.Pereira,Ѷ
free access
Ƶ Neurol. 2017; 74(3):268-274. 10.1001/jamaneurol.2016.5374
This study examines whether treatment with intravenous thrombolysis before mechanical thrombectomy with a stent retriever is beneficial in patients undergoing mechanical thrombectomy.
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Ƶ Neurology
Original Investigation
January 1, 2017
Leticia C.Rebello,Ѷ; Mehdi Bouslama,Ѷ; Diogo C.Haussen,Ѷ; Seena Dehkharghani,Ѷ; Jonathan A.Grossberg,Ѷ; Samir Belagaje,Ѷ; Michael R.Frankel,Ѷ; Raul G.Nogueira,Ѷ
free access
Ƶ Neurol. 2017; 74(1):34-40. 10.1001/jamaneurol.2016.3954
This case-control study compares the outcomes of patients following stroke with large baseline ischemic cores on computed tomographic perfusion undergoing endovascular therapy with the outcomes of matched controls who had medical care alone.
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JAMA
Original Investigation
September 27, 2016
Jeffrey L.Saver,Ѷ; Mayank Goyal,Ѷ; Aad van der Lugt,Ѷ; Bijoy K.Menon,Ѷ; Charles B. L. M.Majoie,Ѷ; Diederik W.Dippel,Ѷ; Bruce C.Campbell,Ѷ, PhD; Raul G.Nogueira,Ѷ; Andrew M.Demchuk,Ѷ; Alejandro Tomasello,Ѷ; Pere Cardona,Ѷ; Thomas G.Devlin,Ѷ; Donald F.Frei,Ѷ; Richard du Mesnil de Rochemont,Ѷ; Olvert A.Berkhemer,Ѷ; Tudor G.Jovin,Ѷ; Adnan H.Siddiqui,Ѷ, PhD; Wim H.van Zwam,Ѷ; Stephen M.Davis,Ѷ; Carlos Castaño,Ѷ; Biggya L.Sapkota,Ѷ; Puck S.Fransen,Ѷ; Carlos Molina,Ѷ; Robert J.van Oostenbrugge,Ѷ; Ángel Chamorro,Ѷ; Hester Lingsma, PhD; Frank L.Silver,Ѷ; Geoffrey A.Donnan,Ѷ; Ashfaq Shuaib,Ѷ; Scott Brown, PhD; Bruce Stouch, PhD; Peter J.Mitchell,Ѷ; Antoni Davalos,Ѷ; Yvo B. W. E. M.Roos,Ѷ; Michael D.Hill,Ѷ, MS; for the HERMES Collaborators
free access
has multimedia
JAMA. 2016; 316(12):1279-1289. 10.1001/jama.2016.13647
This meta-analysis of trials comparing treatment of acute ischemic stroke with vs without endovascular thrombectomy characterizes the threshold time after which treatment is no longer beneficial.
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Ƶ Neurology
Original Investigation
February 1, 2014
Fabricio O.Lima,Ѷ, MPH; Karen L.Furie,Ѷ, MPH; Gisele S.Silva,Ѷ, PhD; Michael H.Lev,Ѷ; Érica C. S.Camargo,Ѷ, PhD; Aneesh B.Singhal,Ѷ; Gordon J.Harris, PhD; Elkan F.Halpern, PhD; Walter J.Koroshetz,Ѷ; Wade S.Smith,Ѷ; Raul G.Nogueira,Ѷ
free access
Ƶ Neurol. 2014; 71(2):151-157. 10.1001/jamaneurol.2013.5007
In a prospective cohort study at 2 university-based hospitals between 2003 and 2005, Lima and coauthors investigate the outcomes of patients who had an acute ischemic stroke attributable to an anterior circulation proximal intracranial arterial occlusion. See the editorial by Yahgi and Marshall.
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Ƶ Neurology
Original Investigation
July 1, 2013
Srikant Rangaraju, MD; Kumiko Owada, MD; Ali Reza Noorian, MD; Raul G. Nogueira, MD; Fadi Nahab, MD; Brenda A. Glenn, RN, BSN, ACNP; Samir R. Belagaje, MD; Aaron M. Anderson, MD; Michael R. Frankel, MD; Rishi Gupta, MD
free access
Ƶ Neurol. 2013; 70(7):831-836. 10.1001/jamaneurol.2013.413
In a retrospective cohort study, Rangaraju and coauthors assess whether patients with intracranial large-vessel occlusions who received intra-arterial therapy have smaller final infarct volumes than patients who received either intravenous tissue plasminogen activator therapy or no reperfusion therapy. See the editorial by Adams and Froehler.
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Ƶ Neurology
History of Neurology: Seminal Citations
December 1, 2004
Raul G. Nogueira, MD; Bryan Traynor, MD, MRCPI
Arch Neurol. 2004; 61(12):1974-1977. 10.1001/archneur.61.12.1974