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  • Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial

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    JAMA. 2024; 331(17):1460-1470. 10.1001/jama.2024.4011

    This secondary analysis of a randomized clinical trial assesses whether screening for prostate-specific antigen reduces prostate cancer mortality at 15-year follow-up.

  • Analysis of Maternal Prenatal Weight and Offspring Cognition and Behavior: Results From the Promotion of Breastfeeding Intervention Trial (PROBIT) Cohort

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    ÁñÁ«ÊÓƵ Netw Open. 2021; 4(8):e2121429. 10.1001/jamanetworkopen.2021.21429

    This cohort study examines association of maternal prenatal body mass index with cognition and behavior of offspring born full-term.

  • Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer

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    JAMA. 2020; 323(7):646-655. 10.1001/jama.2020.0150

    This study uses mendelian randomization to estimate the associations between genetic variants related to reduced HMG-CoA reductase activity and epithelial ovarian cancer in the general population and in BRCA1/2 mutation carriers.

  • Association of Weight for Length vs Body Mass Index During the First 2 Years of Life With Cardiometabolic Risk in Early Adolescence

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    ÁñÁ«ÊÓƵ Netw Open. 2018; 1(5):e182460. 10.1001/jamanetworkopen.2018.2460

    This study of birth cohorts from the United States and Belarus examines whether weight for length or body mass index more accurately estimates future cardiometabolic outcomes in children younger than 2 years.

  • Power of a Trial Investigating a Low-Intensity PSA-Based Screening Intervention—Reply

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    JAMA. 2018; 320(6):600-601. 10.1001/jama.2018.7335
  • Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial

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    JAMA. 2018; 319(9):883-895. 10.1001/jama.2018.0154

    This cluster randomized trial evaluates the effect of a single prostate-specific antigen (PSA) screening test on 10-year prostate cancer–specific mortality among men aged 50 to 69 years treated at UK primary care practices.

  • Effect of an Intervention to Promote Breastfeeding on Asthma, Lung Function, and Atopic Eczema at Age 16 Years: Follow-up of the PROBIT Randomized Trial

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    JAMA Pediatr. 2018; 172(1):e174064. 10.1001/jamapediatrics.2017.4064

    This follow-up to a randomized clinical trial evaluates the effect of intervention promoting breastfeeding at the child’s birth on asthma, atopic eczema, and lung function after 16 years.

  • Effects of Promoting Long-term, Exclusive Breastfeeding on Adolescent Adiposity, Blood Pressure, and Growth Trajectories: A Secondary Analysis of a Randomized Clinical Trial

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    JAMA Pediatr. 2017; 171(7):e170698. 10.1001/jamapediatrics.2017.0698

    This secondary analysis of a randomized clinical trial investigates the effects of a breastfeeding promotion intervention on adiposity and blood pressure at age 16 years and on longitudinal growth trajectories from birth.

  • Indication of Measures of Uncertainty for Statistical Significance in Abstracts of Published Oncology Trials: A Systematic Review and Meta-analysis

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    ÁñÁ«ÊÓƵ Netw Open. 2019; 2(12):e1917530. 10.1001/jamanetworkopen.2019.17530

    This systematic review and meta-analysis examines the expression of uncertainty in abstracts of published oncology randomized clinical trials.

  • Effect of Aflibercept Plus Modified FOLFOX6 Induction Chemotherapy Before Standard Chemoradiotherapy and Surgery in Patients With High-Risk Rectal Adenocarcinoma: The GEMCAD 1402 Randomized Clinical Trial

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    JAMA Oncol. 2019; 5(11):1566-1573. 10.1001/jamaoncol.2019.2294

    This phase 2 randomized clinical trial evaluates the effect of modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX) induction chemotherapy with or without aflibercept before chemoradiotherapy and total mesorectal excision surgery in patients with high-risk, locally advanced rectal adenocarcinoma.

  • Effects of Promoting Longer-term and Exclusive Breastfeeding on Adiposity and Insulin-like Growth Factor-I at Age 11.5 Years: A Randomized Trial

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    JAMA. 2013; 309(10):1005-1013. 10.1001/jama.2013.167
    In a cluster-randomized controlled trial of 17 046 breastfeeding mother-infant pairs in 31 hospitals in Belarus, Martin and colleagues investigate the effects of increased duration and exclusivity of breastfeeding on child adiposity and circulating insulin-like growth factor (IGF)-I.
  • Interaction of Target Oxygen Saturation, Bronchopulmonary Dysplasia, and Pulmonary Hypertension in Small for Gestational Age Preterm Neonates—Reply

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    JAMA Pediatr. 2016; 170(8):808-808. 10.1001/jamapediatrics.2016.0998
  • Association of Oxygen Target and Growth Status With Increased Mortality in Small for Gestational Age Infants: Further Analysis of the Surfactant, Positive Pressure and Pulse Oximetry Randomized Trial

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    JAMA Pediatr. 2016; 170(3):292-294. 10.1001/jamapediatrics.2015.3794

    This post hoc study assesses whether there is an association between oxygen target and growth status.

  • Oxycodone for Cancer-Related Pain: Meta-analysis of Randomized Controlled Trials

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    Arch Intern Med. 2006; 166(8):837-843. 10.1001/archinte.166.8.837
  • Effect of Vitamin D 3 on Asthma Treatment Failures in Adults With Symptomatic Asthma and Lower Vitamin D Levels: The VIDA Randomized Clinical Trial

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    JAMA. 2014; 311(20):2083-2091. 10.1001/jama.2014.5052

    Castro and coauthors report the effect of vitamin D3 supplementation on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels.

  • Comparison of Physician-, Biomarker-, and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma: The BASALT Randomized Controlled Trial

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    JAMA. 2012; 308(10):987-997. 10.1001/2012.jama.10893
    Calhoun and coauthors compared physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma in the Best Adjustment Strategy for Asthma in the Long Term (BASALT) randomized controlled trial. In an accompanying Editorial, Reibman and O’Connor discuss inhaled corticosteroid dose adjustment in mild persistent asthma.
  • Long-Acting β 2 -Agonist Monotherapy vs Continued Therapy With Inhaled Corticosteroids in Patients With Persistent Asthma: A Randomized Controlled Trial

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    JAMA. 2001; 285(20):2583-2593. 10.1001/jama.285.20.2583
  • Inhaled Corticosteroid Reduction and Elimination in Patients With Persistent Asthma Receiving Salmeterol: A Randomized Controlled Trial

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    JAMA. 2001; 285(20):2594-2603. 10.1001/jama.285.20.2594
  • Cardiorespiratory Events Recorded on Home Monitors: Comparison of Healthy Infants With Those at Increased Risk for SIDS

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    JAMA. 2001; 285(17):2199-2207. 10.1001/jama.285.17.2199
  • The Detection of Sleep Apnea in the Awake Patient: The 'Saw-Tooth' Sign

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    JAMA. 1981; 245(23):2414-2418. 10.1001/jama.1981.03310480030021