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  • Associations Between Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments

    Abstract Full Text
    online first
    JAMA. 2024; 10.1001/jama.2024.4175

    This study examines the strength of association between surrogate markers used as primary end points in clinical trials to support FDA approval of drugs treating nononcologic chronic diseases and clinical outcomes.

  • Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial

    Abstract Full Text
    open access has multimedia
    ÁñÁ«ÊÓƵ Neurol. 2021; 78(6):687-698. 10.1001/jamaneurol.2021.0538

    This randomized clinical trial evaluates whether 10-kHz spinal cord stimulation improves outcomes for patients with painful diabetic neuropathy refractory to conventional medical management.

  • Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse: An Individual Patient Data Meta-analysis From Randomized Trials

    Abstract Full Text
    free access
    JAMA Psychiatry. 2016; 73(6):565-574. 10.1001/jamapsychiatry.2016.0076

    This meta-analysis examines individual patient data to discover the efficacy of mindfulness-based cognitive therapy compared with usual care and other active treatments, including antidepressants, in treating those with recurrent depression.

  • School-Based Violence Prevention Programs: Systematic Review of Secondary Prevention Trials

    Abstract Full Text
    free access
    Arch Pediatr Adolesc Med. 2002; 156(8):752-762. 10.1001/archpedi.156.8.752