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  • 榴莲视频 Neurology Original Investigation
    March 11, 2024

    Clopidogrel Plus Aspirin vs Aspirin Alone in Patients With Acute Mild to Moderate Stroke: The ATAMIS Randomized Clinical Trial

    Hui-Sheng听Chen,听MD; Yu听Cui,听PhD; Xin-Hong听Wang,听MD; Yu-Tong听Ma,听MM; Jing听Han,听MM; Ying-Jie听Duan,听MM; Jiang听Lu,听BSM; Li-Ying听Shen,听BSM; Yong听Liang,听BSM; Wei-Zhong听Wang,听BSM; Hui听Wang,听MM; Yong听Zhao,听BSM; Jin-Tao听Zhang,听MD; Yu-Lin听Song,听MM; Xiao-Mei听He,听BSM; Run-Hui听Li,听MM; Ding-Bo听Tao,听MM; Jing听Li,听BSM; Shu-Man听Huang,听BSM; Ni听Wang,听MM; Mei听Hong,听BSM; Chong听Meng,听MM; Wei听Zhang,听MM; Duo-Lao听Wang,听PhD; Thanh N.听Nguyen,听MD; ATAMIS investigators
    Abstract Full Text
    榴莲视频 Neurol. 2024; 81(5):450-460. 10.1001/jamaneurol.2024.0146

    This randomized clinical trial evaluates the use of dual vs single antiplatelet therapy in the treatment of patients with mild to moderate ischemic stroke.

  • 榴莲视频 Neurology Original Investigation
    November 27, 2023

    Alberta Stroke Program Early Computed Tomography Score, Infarct Core Volume, and Endovascular Therapy Outcomes in Patients With Large Infarct: A Secondary Analysis of the ANGEL-ASPECT Trial

    Dapeng听Sun,听MD, PhD; Xu听Guo,听MD; Thanh N.听Nguyen,听MD; Yuesong听Pan,听PhD; Gaoting听Ma,听MD; Xu听Tong,听MD; Raynald,听MD; Mengxing听Wang,听PhD; Ning听Ma,听MD; Feng听Gao,听MD; Dapeng听Mo,听MD; Xiaochuan听Huo,听MD; Zhongrong听Miao,听MD; ANGEL-ASPECT Study Group
    Abstract Full Text
    榴莲视频 Neurol. 2023; 81(1):30-38. 10.1001/jamaneurol.2023.4430

    This secondary analysis of the ANGEL-ASPECT randomized clinical trial examines outcomes of endovascular therapy vs medical management across varying Alberta Stroke Program Early Computed Tomography Score (ASPECTS) and infarct core volume strata in patients with large infarct.

  • JAMA Original Investigation
    June 27, 2023

    Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial

    Hui-Sheng听Chen,听MD; Yu听Cui,听PhD; Zhong-He听Zhou,听MD; Hong听Zhang,听BSM; Li-Xia听Wang,听BSM; Wei-Zhong听Wang,听BSM; Li-Ying听Shen,听BSM; Li-Yan听Guo,听MM; Er-Qiang听Wang,听MM; Rui-Xian听Wang,听MM; Jing听Han,听MM; Yu-Ling听Dong,听BSM; Jing听Li,听BSM; Yong-Zhong听Lin,听MD; Qing-Cheng听Yang,听BSM; Li听Zhang,听BSM; Jing-Yu听Li,听MM; Jin听Wang,听BSM; Lei听Xia,听BSM; Guang-Bin听Ma,听BSM; Jiang听Lu,听BSM; Chang-Hao听Jiang,听BSM; Shu-Man听Huang,听BSM; Li-Shu听Wan,听MM; Xiang-Yu听Piao,听MD; Zhuo听Li,听MM; Yan-Song听Li,听MM; Kui-Hua听Yang,听BSM; Duo-Lao听Wang,听PhD; Thanh N.听Nguyen,听MD; ARAMIS Investigators
    Abstract Full Text
    free access
    JAMA. 2023; 329(24):2135-2144. 10.1001/jama.2023.7827

    This randomized trial examines whether dual antiplatelet therapy is noninferior to intravenous thrombolysis among patients with minor nondisabling acute ischemic stroke.

  • 榴莲视频 Network Open Original Investigation Neurology
    March 1, 2023

    Functional and Safety Outcomes of Carotid Artery Stenting and Mechanical Thrombectomy for Large Vessel Occlusion Ischemic Stroke With Tandem Lesions

    Mudassir听Farooqui,听MD, MPH; Osama O.听Zaidat,听MD, MS; Ameer E.听Hassan,听DO; Darko听Quispe-Orozco,听MD; Nils听Petersen,听MD; Afshin A.听Divani,听PhD; Marc听Ribo,听MD, PhD; Michael听Abraham,听MD; Johanna听Fifi,听MD; Waldo R.听Guerrero,听MD; Amer M.听Malik,听MD, MBA; James E.听Siegler,听MD; Thanh N.听Nguyen,听MD; Sunil听Sheth,听MD; Albert J.听Yoo,听MD, PhD; Guillermo听Linares,听MD; Nazli听Janjua,听MD; Milagros听Galecio-Castillo,听MD; Wondewossen G.听Tekle,听MD; Victor M.听Ringheanu,听BA; Marion听Oliver,听MD; Giana听Dawod,听MD; Jessica听Kobsa,听BA; Ayush听Prasad,听BA; Asad听Ikram,听MD; Eugene听Lin,听MD; Kristine听Below,听BA; Cynthia B.听Zevallos,听MD; Marta Oliv茅听Gadea,听MD; Abid听Qureshi,听MD; Andres听Dajles,听MS; Stavros听Matsoukas,听MD; Ameena听Rana,听MD; Mohamad听Abdalkader,听MD; Sergio听Salazar-Marioni,听MD; Jazba听Soomro,听MD; Weston听Gordon,听MD; Juan听Vivanco-Suarez,听MD; Charoskhon听Turabova,听MD; Maxim听Mokin,听MD; Dileep R.听Yavagal,听MD; Mouhammad A.听Jumaa,听MD; Santiago听Ortega-Gutierrez,听MD, MSc
    Abstract Full Text
    open access
    榴莲视频 Netw Open. 2023; 6(3):e230736. 10.1001/jamanetworkopen.2023.0736

    This cross-sectional study evaluates the clinical and technical outcomes of carotid artery stenting vs no stenting during mechanical thrombectomy in patients with acute large vessel occlusion strokes and concomitant tandem lesions.

  • 榴莲视频 Neurology Original Investigation
    November 8, 2021

    Noncontrast Computed Tomography vs Computed Tomography Perfusion or Magnetic Resonance Imaging Selection in Late Presentation of Stroke With Large-Vessel Occlusion

    Thanh N.听Nguyen,听MD; Mohamad听Abdalkader,听MD; Simon听Nagel,听MD; Muhammad M.听Qureshi,听MPH; Marc听Ribo,听MD, PhD; Francois听Caparros,听MD; Diogo C.听Haussen,听MD; Mahmoud H.听Mohammaden,听MD, MSc; Sunil A.听Sheth,听MD; Santiago听Ortega-Gutierrez,听MD, MSc; James E.听Siegler,听MD; Syed听Zaidi,听MD; Marta听Olive-Gadea,听MD; Hilde听Henon,听MD, PhD; Markus A.听M枚hlenbruch,听MD; Alicia C.听Castonguay,听PhD; Stefania听Nannoni,听MD; Johannes听Kaesmacher,听MD; Ajit S.听Puri,听MD; Fatih听Seker,听MD; Mudassir听Farooqui,听MD, MPH; Sergio听Salazar-Marioni,听MD; Anna L.听Kuhn,听MD; Artem听Kaliaev,听MD; Behzad听Farzin,听MD; William听Boisseau,听MD; Hesham E.听Masoud,听MD; Carlos Ynigo听Lopez,听MD; Ameena听Rana,听MD; Samer Abdul听Kareem,听MD; Anvitha听Sathya; Piers听Klein; Mohammad W.听Kassem,听MD, MBA; Peter A.听Ringleb,听MD; Charlotte听Cordonnier,听MD, PhD; Jan听Gralla,听MD; Urs听Fischer,听MD, MSc; Patrik听Michel,听MD; Tudor G.听Jovin,听MD; Jean听Raymond,听MD; Osama O.听Zaidat,听MD, MS; Raul G.听Nogueira,听MD
    Abstract Full Text
    open access is active quiz
    榴莲视频 Neurol. 2021; 79(1):22-31. 10.1001/jamaneurol.2021.4082

    This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.

  • JAMA Original Investigation
    February 7, 2024

    Endovascular Thrombectomy for Large Ischemic Stroke Across Ischemic Injury and Penumbra Profiles

    Amrou听Sarraj,听MD; Ameer E.听Hassan,听DO; Michael G.听Abraham,听MD; Santiago听Ortega-Gutierrez,听MD; Scott E.听Kasner,听MD; Muhammad Shazam听Hussain,听MD; Michael听Chen,听MD; Leonid听Churilov,听PhD; Hannah听Johns,听PhD; Clark W.听Sitton,听MD; Vignan听Yogendrakumar,听MD; Felix C.听Ng,听PhD; Deep K.听Pujara,听MBBS; Spiros听Blackburn,听MD; Sophia听Sundararajan,听MD; Yin C.听Hu,听MD; Nabeel A.听Herial,听MD; Juan F.听Arenillas,听MD, PhD; Jenny P.听Tsai,听MD; Ronald F.听Budzik,听MD; William J.听Hicks,听MD; Osman听Kozak,听MD; Bernard听Yan,听MBBS; Dennis J.听Cordato,听PhD; Nathan W.听Manning,听MBBS; Mark W.听Parsons,听PhD; Andrew听Cheung,听MBBS; Ricardo A.听Hanel,听MD; Amin N.听Aghaebrahim,听MD; Teddy Y.听Wu,听PhD; Pere Cardona听Portela,听MD; Chirag D.听Gandhi,听MD; Fawaz听Al-Mufti,听MD; Natalia听P茅rez de la Ossa,听MD, PhD; Joanna D.听Schaafsma,听MD, PhD; Jordi听Blasco,听MD, PhD; Navdeep听Sangha,听MD; Steven听Warach,听MD; Timothy J.听Kleinig,听PhD; Faris听Shaker,听MBChB; Faisal听Al Shaibi,听MD; Gabor听Toth,听MD; Mohammad A.听Abdulrazzak,听MD; Gagan听Sharma,听MS; Abhishek听Ray,听MD; Jeffrey听Sunshine,听MD, PhD; Amanda听Opaskar,听MD; Kelsey R.听Duncan,听MD; Wei听Xiong,听MD; Edgar A.听Samaniego,听MD; Laith听Maali,听MD; Colleen G.听Lechtenberg,听MD; Arturo听Ren煤,听MD; Nirav听Vora,听MD; Thanh听Nguyen,听MD; Johanna T.听Fifi,听MD; Stavropoula I.听Tjoumakaris,听MD; Pascal听Jabbour,听MD; Georgios听Tsivgoulis,听MD; Vitor Mendes听Pereira,听MD; Maarten G.听Lansberg,听MD; Michael听DeGeorgia,听MD; Cathy A.听Sila,听MD; Nicholas听Bambakidis,听MD; Michael D.听Hill,听MD; Stephen M.听Davis,听MD; Lawrence听Wechsler,听MD; James C.听Grotta,听MD; Marc听Ribo,听MD; Greg W.听Albers,听MD; Bruce C.听Campbell,听PhD; SELECT2 Investigators
    Abstract Full Text
    JAMA. 2024; 331(9):750-763. 10.1001/jama.2024.0572

    This exploratory analysis of the SELECT2 trial assesses the relationship between imaging estimates of irreversibly injured brain (core) and at-risk regions (mismatch) and the association of mismatch with clinical outcomes and endovascular treatment effect in adult patients with acute ischemic stroke due to occlusion of the internal carotid or middle cerebral artery and large ischemic core in 31 global centers between October 2019 and September 2022.

  • 榴莲视频 Neurology Original Investigation
    February 8, 2024

    Endovascular Thrombectomy Treatment Effect in Direct vs Transferred Patients With Large Ischemic Strokes: A Prespecified Analysis of the SELECT2 Trial

    Amrou听Sarraj,听MD; Michael D.听Hill,听MD; M. Shazam听Hussain,听MD; Michael G.听Abraham,听MD; Santiago听Ortega-Gutierrez,听MD; Michael听Chen,听MD; Scott E.听Kasner,听MD; Leonid听Churilov,听PhD; Deep K.听Pujara,听MBBS; Hannah听Johns,听PhD; Spiros听Blackburn,听MD; Sophia听Sundararajan,听MD; Yin C.听Hu,听MD; Nabeel A.听Herial,听MD; Ronald F.听Budzik,听MD; William J.听Hicks,听MD; Juan F.听Arenillas,听MD, PhD; Jenny P.听Tsai,听MD; Osman听Kozak,听MD; Dennis J.听Cordato,听PhD; Ricardo A.听Hanel,听MD; Teddy Y.听Wu,听PhD; Pere Cardona听Portela,听MD; Chirag D.听Gandhi,听MD; Fawaz听Al-Mufti,听MD; Laith听Maali,听MD; Daniel听Gibson,听MD; Natalia听P茅rez de la Ossa,听MD, PhD; Joanna D.听Schaafsma,听MD; Jordi听Blasco,听MD, PhD; Navdeep听Sangha,听MD; Steven听Warach,听MD; Timothy J.听Kleinig,听PhD; Faris听Shaker,听MBChB; Clark W.听Sitton,听MD; Thanh听Nguyen,听MD; Johanna T.听Fifi,听MD; Pascal听Jabbour,听MD; Anthony听Furlan,听MD; Maarten G.听Lansberg,听MD; Georgios听Tsivgoulis,听MD; Cathy听Sila,听MD; Nicholas听Bambakidis,听MD; Stephen听Davis,听MD; Lawrence听Wechsler,听MD; Greg W.听Albers,听MD; James C.听Grotta,听MD; Marc听Ribo,听MD; Bruce C.听Campbell,听MD; Ameer E.听Hassan,听MD; SELECT2 Investigators; SELECT2 Collaborators
    Abstract Full Text
    榴莲视频 Neurol. 2024; 81(4):327-335. 10.1001/jamaneurol.2024.0206

    This prespecified analysis of the SELECT2 trial assesses endovascular thrombectomy treatment effects in transferred vs directly presenting patients and evaluates the association between transfer times and neuroimaging changes with endovascular thrombectomy clinical outcomes.

  • 榴莲视频 Network Open Original Investigation Statistics and Research Methods
    August 29, 2022

    A Crowdsourcing Approach to Develop Machine Learning Models to Quantify Radiographic Joint Damage in Rheumatoid Arthritis

    Dongmei听Sun,听PhD, MSPH; Thanh M.听Nguyen,听PhD; Robert J.听Allaway,听PhD; Jelai听Wang,听BS; Verena听Chung,听MS; Thomas V.听Yu,听BS; Michael听Mason,听PhD; Isaac听Dimitrovsky,听PhD; Lars听Ericson,听PhD; Hongyang听Li,听PhD; Yuanfang听Guan,听PhD; Ariel听Israel,听PhD; Alex听Olar,听MS; Balint Armin听Pataki,听PhD; Gustavo听Stolovitzky,听PhD; Justin听Guinney,听PhD; Percio S.听Gulko,听MD; Mason B.听Frazier,听MD; Jake Y.听Chen,听PhD; James C.听Costello,听PhD; S. Louis听Bridges听Jr,听MD, PhD; RA2-DREAM Challenge Community
    Abstract Full Text
    open access
    榴莲视频 Netw Open. 2022; 5(8):e2227423. 10.1001/jamanetworkopen.2022.27423

    This diagnostic/prognostic study presents assesses machine learning algorithms submitted to an international crowdsourcing contest to develop methos to automatically quantify radiographic evidence of damage in patients with rheumatoid arthritis (RA).