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  • JAMA Cardiology Original Investigation
    February 21, 2024

    Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV: Mechanistic Substudy of the REPRIEVE Randomized Clinical Trial

    Michael T.听Lu,听MD, MPH; Heather听Ribaudo,听PhD; Borek听Foldyna,听MD; Markella V.听Zanni,听MD; Thomas听Mayrhofer,听PhD; Julia听Karady,听MD, PhD; Jana听Taron,听MD; Kathleen V.听Fitch,听MSN; Sara听McCallum,听MPH; Tricia H.听Burdo,听PhD; Kayla听Paradis,听MBA; Sandeep S.听Hedgire,听MD; Nandini M.听Meyersohn,听MD; Christopher听DeFilippi,听MD; Carlos D.听Malvestutto,听MD, MPH; Audra听Sturniolo,听MS; Marissa听Diggs,听BA; Sue听Siminski,听MBA; Gerald S.听Bloomfield,听MD; Beverly听Alston-Smith,听MD; Patrice听Desvigne-Nickens,听MD; Edgar T.听Overton,听MD; Judith S.听Currier,听MD; Judith A.听Aberg,听MD; Carl J.听Fichtenbaum,听MD; Udo听Hoffmann,听MD, MPH; Pamela S.听Douglas,听MD; Steven K.听Grinspoon,听MD; REPRIEVE Trial Writing Group
    Abstract Full Text
    open access has multimedia
    JAMA Cardiol. 2024; 9(4):323-334. 10.1001/jamacardio.2023.5661

    This substudy of a randomized clinical trial investigates the effects of pitavastatin on noncalcified coronary artery plaque using coronary computed tomography angiography and on inflammatory biomarkers as potential mechanisms for major adverse cardiovascular event prevention.

  • JAMA Cardiology Original Investigation
    December 22, 2021

    Differences in Cardiovascular Risk, Coronary Artery Disease, and Cardiac Events Between Black and White Individuals Enrolled in the PROMISE Trial

    Lili听Zhang,听MD, ScM; Devvora听Olalere,听MS; Thomas听Mayrhofer,听PhD; Daniel O.听Bittner,听MD; Hamed听Emami,听MD; Nina M.听Meyersohn,听MD; Stefan B.听Puchner,听MD; Aiden听Abidov,听MD, PhD; Jamaluddin听Moloo,听MD, MPH; Rowena J.听Dolor,听MD, MHS; Daniel B.听Mark,听MD; Maros听Ferencik,听MD; Udo听Hoffmann,听MD, MPH; Pamela S.听Douglas,听MD; Michael T.听Lu,听MD, MPH
    Abstract Full Text
    free access
    JAMA Cardiol. 2021; 7(3):259-267. 10.1001/jamacardio.2021.5340

    This cohort study compares the risk factors and noninvasive testing outcomes of Black and White persons with stable chest pain.

  • 榴莲视频 Network Open Original Investigation Cardiology
    June 29, 2021

    Assessment of Coronary Artery Disease With Computed Tomography Angiography and Inflammatory and Immune Activation Biomarkers Among Adults With HIV Eligible for Primary Cardiovascular Prevention

    Udo听Hoffmann,听MD, MPH; Michael T.听Lu,听MD, MPH; Borek听Foldyna,听MD; Markella V.听Zanni,听MD; Julia听Karady,听MD; Jana听Taron,听MD; Bingxue K.听Zhai,听MS; Tricia听Burdo,听PhD; Kathleen V.听Fitch,听MSN; Emma M.听Kileel,听MPH; Kenneth听Williams,听PhD; Carl J.听Fichtenbaum,听MD; Edgar T.听Overton,听MD; Carlos听Malvestutto,听MD; Judith听Aberg,听MD; Judith听Currier,听MD; Craig A.听Sponseller,听MD; Kathleen听Melbourne,听PharmD; Michelle听Floris-Moore,听MD; Cornelius听Van Dam,听MD; Michael C.听Keefer,听MD; Susan L.听Koletar,听MD; Pamela S.听Douglas,听MD; Heather听Ribaudo,听PhD; Thomas听Mayrhofer,听PhD; Steven K.听Grinspoon,听MD; REPRIEVE trial
    Abstract Full Text
    open access
    榴莲视频 Netw Open. 2021; 4(6):e2114923. 10.1001/jamanetworkopen.2021.14923

    This cohort study examines the prevalence of coronary artery disease (CAD) among adults with well-controlled HIV and low to moderate risk of atherosclerotic cardiovascular disease using computed tomography angiography and assessment of inflammation and immune activation biomarkers.

  • 榴莲视频 Network Open Original Investigation Health Policy
    December 14, 2020

    Cost-effectiveness Analysis of Anatomic vs Functional Index Testing in Patients With Low-Risk Stable Chest Pain

    J煤lia听Kar谩dy,听MD; Thomas听Mayrhofer,听PhD; Alexander听Ivanov,听BS; Borek听Foldyna,听MD; Michael T.听Lu,听MD, MPH; Maros听Ferencik,听MD, PhD, MCR; Amit听Pursnani,听MD; Michael听Salerno,听MD, PhD, MS; James E.听Udelson,听MD; Daniel B.听Mark,听MD, MPH; Pamela S.听Douglas,听MD; Udo听Hoffmann,听MD, MPH
    Abstract Full Text
    open access
    榴莲视频 Netw Open. 2020; 3(12):e2028312. 10.1001/jamanetworkopen.2020.28312

    This economic evaluation determines whether anatomic approaches are cost-effective compared with functional tests for the assessment of low-risk stable chest pain.

  • 榴莲视频 Network Open Original Investigation Health Informatics
    July 19, 2019

    Deep Learning to Assess Long-term Mortality From Chest Radiographs

    Michael T.听Lu,听MD, MPH; Alexander听Ivanov,听BS; Thomas听Mayrhofer,听PhD; Ahmed听Hosny,听MS; Hugo J. W. L.听Aerts,听PhD; Udo听Hoffmann,听MD, MPH
    Abstract Full Text
    open access has multimedia
    榴莲视频 Netw Open. 2019; 2(7):e197416. 10.1001/jamanetworkopen.2019.7416

    This prognostic study develops and tests a convoluted neural network (CXR-risk) to predict long-term mortality from chest radiographs.

  • JAMA Cardiology Original Investigation
    February 1, 2018

    Use of High-Risk Coronary Atherosclerotic Plaque Detection for Risk Stratification of Patients With Stable Chest Pain: A Secondary Analysis of the PROMISE Randomized Clinical Trial

    Maros听Ferencik,听MD, PhD, MCR; Thomas听Mayrhofer,听PhD; Daniel O.听Bittner,听MD; Hamed听Emami,听MD; Stefan B.听Puchner,听MD; Michael T.听Lu,听MD, MPH; Nandini M.听Meyersohn,听MD; Alexander V.听Ivanov,听BS; Elizabeth C.听Adami,听BS; Manesh R.听Patel,听MD; Daniel B.听Mark,听MD, MPH; James E.听Udelson,听MD; Kerry L.听Lee,听PhD; Pamela S.听Douglas,听MD; Udo听Hoffmann,听MD, MPH
    Abstract Full Text
    free access
    JAMA Cardiol. 2018; 3(2):144-152. 10.1001/jamacardio.2017.4973

    This nested observational cohort study seeks to determine whether high-risk plaque detected by coronary computed tomographic angiography was independently associated with major adverse cardiovascular events.