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Ƶ Neurology
Original Investigation
July 31, 2023
Vicky Chalos,Ѷ, PhD; Esmee Venema,Ѷ, PhD; Maxim J. H. L.Mulder,Ѷ, PhD; Bob Roozenbeek,Ѷ, PhD; Ewout W.Steyerberg, PhD; Marieke J. H.Wermer,Ѷ, PhD; Geert J.Lycklama à Nijeholt,Ѷ, PhD; H. Bart van der Worp,Ѷ, PhD; Mayank Goyal,Ѷ; Bruce C. V.Campbell, PhD; Keith W.Muir,Ѷ; Francis Guillemin,Ѷ; Serge Bracard,Ѷ; Philip White,Ѷ; Antoni Dávalos,Ѷ; Tudor G.Jovin,Ѷ; Michael D.Hill,Ѷ; Peter J.Mitchell, MMed; Andrew M.Demchuk,Ѷ; Jeffrey L.Saver,Ѷ; Aad van der Lugt,Ѷ, PhD; Scott Brown, PhD; Diederik W. J.Dippel,Ѷ; Hester F.Lingsma, PhD; HERMES CollaboratorsMR CLEAN Registry Investigators
Ƶ Neurol. 2023; 80(9):940-948. 10.1001/jamaneurol.2023.2392
This prognostic study investigates the effectiveness of a prognostic tool to predict the functional outcome of individual patients after endovascular treatment for ischemic stroke.
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Ƶ Neurology
Original Investigation
June 20, 2023
Macarena Hernández-Jiménez, PhD; Francisco Abad-Santos,Ѷ; Ian Cotgreave, PhD; Jaime Gallego,Ѷ; Bernd Jilma,Ѷ; Alan Flores,Ѷ; Tudor G.Jovin,Ѷ; José Vivancos,Ѷ; María Hernández-Pérez,Ѷ; Carlos A.Molina,Ѷ; Joan Montaner,Ѷ; Joaquín Casariego,Ѷ; Mads Dalsgaard,Ѷ; David S.Liebeskind,Ѷ; Erik Cobo,Ѷ; Mar Castellanos,Ѷ; Pere Cardona Portela,Ѷ; Jaime Masjuán,Ѷ; Francisco Moniche,Ѷ; José Ignacio Tembl,Ѷ; Mikel Terceño Izaga,Ѷ; Juan F.Arenillas,Ѷ; Patricia Calleja,Ѷ; Jean Marc Olivot,Ѷ; Lionel Calviere,Ѷ; Hilde Henon,Ѷ; Mikael Mazighi,Ѷ; David Piñeiro, PhD; Marco Pugliese,Ѷ; Victor M.González, PhD; Maria Angeles Moro, PhD; Alvaro Garcia-Tornel,Ѷ; Ignacio Lizasoain, PhD; Marc Ribo,Ѷ
Ƶ Neurol. 2023; 80(8):779-788. 10.1001/jamaneurol.2023.1660
This randomized clinical trial investigates the safety and efficacy of ApTOLL as a neuroprotectant drug for patients with ischemic stroke when given in combination with endovascular treatment.
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JAMA
Original Investigation
May 5, 2022
Natalia Pérez de la Ossa, PhD; Sònia Abilleira, PhD; Tudor G.Jovin, PhD; Álvaro García-Tornel, PhD; Xavier Jimenez, PhD; Xabier Urra, PhD; Pere Cardona,Ѷ; Dolores Cocho, PhD; Francisco Purroy, PhD; Joaquin Serena, PhD; Luis San Román Manzanera, PhD; Rosa Maria Vivanco-Hidalgo, PhD; Mercè Salvat-Plana, RN; Angel Chamorro, PhD; Miquel Gallofré, PhD; Carlos A.Molina, PhD; Erik Cobo, PhD; Antoni Davalos, PhD; Marc Ribo, PhD; RACECAT Trial Investigators
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JAMA. 2022; 327(18):1782-1794. 10.1001/jama.2022.4404
This randomized trial assesses the effect of transportation to a local stroke center vs directly to a thrombectomy-capable referral center on 90-day disability among patients with acute large-vessel occlusion stroke attended by emergency medical services in areas where the closest local stroke center was not capable of performing thrombectomy.
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Ƶ Neurology
Original Investigation
November 8, 2021
Thanh N.Nguyen,Ѷ; Mohamad Abdalkader,Ѷ; Simon Nagel,Ѷ; Muhammad M.Qureshi, MPH; Marc Ribo,Ѷ, PhD; Francois Caparros,Ѷ; Diogo C.Haussen,Ѷ; Mahmoud H.Mohammaden,Ѷ, MSc; Sunil A.Sheth,Ѷ; Santiago Ortega-Gutierrez,Ѷ, MSc; James E.Siegler,Ѷ; Syed Zaidi,Ѷ; Marta Olive-Gadea,Ѷ; Hilde Henon,Ѷ, PhD; Markus A.Möhlenbruch,Ѷ; Alicia C.Castonguay, PhD; Stefania Nannoni,Ѷ; Johannes Kaesmacher,Ѷ; Ajit S.Puri,Ѷ; Fatih Seker,Ѷ; Mudassir Farooqui,Ѷ, MPH; Sergio Salazar-Marioni,Ѷ; Anna L.Kuhn,Ѷ; Artem Kaliaev,Ѷ; Behzad Farzin,Ѷ; William Boisseau,Ѷ; Hesham E.Masoud,Ѷ; Carlos Ynigo Lopez,Ѷ; Ameena Rana,Ѷ; Samer Abdul Kareem,Ѷ; Anvitha Sathya; Piers Klein; Mohammad W.Kassem,Ѷ, MBA; Peter A.Ringleb,Ѷ; Charlotte Cordonnier,Ѷ, PhD; Jan Gralla,Ѷ; Urs Fischer,Ѷ, MSc; Patrik Michel,Ѷ; Tudor G.Jovin,Ѷ; Jean Raymond,Ѷ; Osama O.Zaidat,Ѷ, MS; Raul G.Nogueira,Ѷ
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is active quiz
Ƶ Neurol. 2021; 79(1):22-31. 10.1001/jamaneurol.2021.4082
This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.
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Ƶ Neurology
Original Investigation
July 26, 2021
Gregory W.Albers,Ѷ; Maarten G.Lansberg,Ѷ, PhD; Scott Brown, PhD; Ashutosh P.Jadhav,Ѷ, PhD; Diogo C.Haussen,Ѷ; Sheila O.Martins,Ѷ, PhD; Leticia C.Rebello,Ѷ; Andrew M.Demchuk,Ѷ; Mayank Goyal,Ѷ, PhD; Marc Ribo,Ѷ; Aquilla S.Turk, DO; David S.Liebeskind,Ѷ; Jeremy J.Heit,Ѷ, PhD; Michael P.Marks,Ѷ; Tudor G.Jovin,Ѷ; Raul G.Nogueira,Ѷ; AURORA Investigators
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Ƶ Neurol. 2021; 78(9):1064-1071. 10.1001/jamaneurol.2021.2319
This pooled analysis uses data from 6 randomized clinical trials to assess the potential benefits of endovascular thrombectomy among patients with ischemic stroke based on 3 baseline imaging profiles.
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Ƶ Neurology
Original Investigation
May 3, 2021
Mohammed A.Almekhlafi,Ѷ, MSc; Mayank Goyal,Ѷ, PhD; Diederik W. J.Dippel,Ѷ; Charles B. L. M.Majoie,Ѷ, PhD; Bruce C. V.Campbell,Ѷ; Keith W.Muir,Ѷ; Andrew M.Demchuk,Ѷ; Serge Bracard,Ѷ; Francis Guillemin,Ѷ, PhD; Tudor G.Jovin,Ѷ; Peter Mitchell,Ѷ; Philip White,Ѷ; Michael D.Hill,Ѷ, MSc; Scott Brown, PhD; Jeffrey L.Saver,Ѷ; HERMES Trialists Collaboration
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Ƶ Neurol. 2021; 78(6):709-717. 10.1001/jamaneurol.2021.1055
This meta-analysis evaluates outcomes along the full health-related quality-of-life range associated with time to endovascular thrombectomy in patients with ischemic stroke.
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Ƶ Neurology
Original Investigation
January 7, 2019
Anna M. M.Boers, PhD; Ivo G. H.Jansen,Ѷ, PhD; Scott Brown, PhD; Hester F.Lingsma, PhD; Ludo F. M.Beenen,Ѷ; Thomas G.Devlin,Ѷ, PhD; Luis San Román,Ѷ, PhD; Ji-Hoe Heo,Ѷ, PhD; Marc Ribó,Ѷ; Mohammed A.Almekhlafi,Ѷ, FRCPC; David S.Liebeskind,Ѷ; Jeanne Teitelbaum,Ѷ; Patricia Cuadras,Ѷ; Richard du Mesnil de Rochemont,Ѷ, PhD; Marine Beaumont, PhD; Martin M.Brown,Ѷ, FRCP; Albert J.Yoo,Ѷ, PhD; Geoffrey A.Donnan,Ѷ; Jean Louis Mas,Ѷ; Catherine Oppenheim, PhD; Richard J.Dowling, MBBS; Thierry Moulin,Ѷ, PhD; Nelly Agrinier,Ѷ, PhD; Demetrius K.Lopes,Ѷ; Lucía Aja Rodríguez,Ѷ; Kars C. J.Compagne, MSc; Fahad S.Al-Ajlan,Ѷ; Jeremy Madigan, MB ChB; Gregory W.Albers,Ѷ; Sebastien Soize,Ѷ; Jordi Blasco,Ѷ, PhD; Stephen M.Davis,Ѷ; Raul G.Nogueira,Ѷ; Antoni Dávalos,Ѷ, PhD; Bijoy K.Menon,Ѷ; Aad van der Lugt,Ѷ, PhD; Keith W.Muir,Ѷ; Yvo B. W. E. M.Roos,Ѷ, PhD; Phil White,Ѷ, PhD; Peter J.Mitchell,Ѷ; Andrew M.Demchuk,Ѷ, FRCPC; Wim H.van Zwam,Ѷ; Tudor G.Jovin,Ѷ; Robert J.van Oostenbrugge,Ѷ, PhD; Diederik W. J.Dippel,Ѷ, PhD; Bruce C. V.Campbell, PhD, FRACP; Francis Guillemin,Ѷ, PhD; Serge Bracard, PhD; Michael D.Hill,Ѷ; Mayank Goyal,Ѷ, FRCPC; Henk A.Marquering, PhD; Charles B. L. M.Majoie,Ѷ, PhD
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Ƶ Neurol. 2019; 76(2):194-202. 10.1001/jamaneurol.2018.3661
This pooled data analysis of 7 randomized clinical trials of thrombectomy for acute ischemic stroke examines whether follow-up infarct volume mediates the relationship between endovascular therapy and functional outcome in patients with acute ischemic stroke.
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Ƶ Neurology
Original Investigation
January 22, 2019
Romain Bourcier,Ѷ; Mayank Goyal,Ѷ; David S.Liebeskind,Ѷ; Keith W.Muir,Ѷ; Hubert Desal,Ѷ; Adnan H.Siddiqui,Ѷ, PhD; Diederik W. J.Dippel,Ѷ; Charles B.Majoie,Ѷ; Wim H.van Zwam,Ѷ; Tudor G.Jovin,Ѷ; Elad I.Levy,Ѷ, MBA; Peter J.Mitchell,Ѷ; Olvert A.Berkhemer,Ѷ; Stephen M.Davis,Ѷ; Imad Derraz,Ѷ; Geoffrey A.Donnan,Ѷ; Andrew M.Demchuk,Ѷ; Robert J.van Oostenbrugge,Ѷ; Michael Kelly,Ѷ; Yvo B.Roos,Ѷ, PhD; Reza Jahan,Ѷ; Aad van der Lugt,Ѷ; Marieke Sprengers,Ѷ; Stephane Velasco,Ѷ; Geert J.Lycklama à Nijeholt,Ѷ; Wagih Ben Hassen,Ѷ; Paul Burns, MB, BCh; Scott Brown,Ѷ; Emmanuel Chabert,Ѷ; Timo Krings,Ѷ; Hana Choe,Ѷ; Christian Weimar,Ѷ; Bruce C. V.Campbell,Ѷ; Gary A.Ford,Ѷ; Marc Ribo,Ѷ; Phil White,Ѷ; Geoffrey C.Cloud,Ѷ; Luis San Roman,Ѷ; Antoni Davalos,Ѷ, PhD; Olivier Naggara,Ѷ; Michael D.Hill,Ѷ; Serge Bracard,Ѷ; for the HERMES Trialists Collaboration
free access
Ƶ Neurol. 2019; 76(4):405-411. 10.1001/jamaneurol.2018.4510
This meta-analysis of individual patient data from 7 randomized clinical trials analyzes the rate of reperfusion after endovascular thrombectomy started at different intervals after symptom onset in patients with acute ischemic stroke.
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Ƶ Neurology
Original Investigation
June 1, 2017
Ashutosh P.Jadhav,Ѷ, PhD; Mehdi Bouslama,Ѷ; Amin Aghaebrahim,Ѷ; Leticia C.Rebello,Ѷ; Matthew T.Starr,Ѷ; Diogo C.Haussen,Ѷ; Manasa Ranginani, MBBS; Matthew K.Whalin,Ѷ, PhD; Tudor G.Jovin,Ѷ; Raul G.Nogueira,Ѷ
free access
Ƶ Neurol. 2017; 74(6):704-709. 10.1001/jamaneurol.2017.0192
This case-control study compares clinical and angiographic outcomes between monitored anesthesia care and general anesthesia in patients presenting with vertebrobasilar occlusion strokes.
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JAMA
Original Investigation
September 27, 2016
Jeffrey L.Saver,Ѷ; Mayank Goyal,Ѷ; Aad van der Lugt,Ѷ; Bijoy K.Menon,Ѷ; Charles B. L. M.Majoie,Ѷ; Diederik W.Dippel,Ѷ; Bruce C.Campbell,Ѷ, PhD; Raul G.Nogueira,Ѷ; Andrew M.Demchuk,Ѷ; Alejandro Tomasello,Ѷ; Pere Cardona,Ѷ; Thomas G.Devlin,Ѷ; Donald F.Frei,Ѷ; Richard du Mesnil de Rochemont,Ѷ; Olvert A.Berkhemer,Ѷ; Tudor G.Jovin,Ѷ; Adnan H.Siddiqui,Ѷ, PhD; Wim H.van Zwam,Ѷ; Stephen M.Davis,Ѷ; Carlos Castaño,Ѷ; Biggya L.Sapkota,Ѷ; Puck S.Fransen,Ѷ; Carlos Molina,Ѷ; Robert J.van Oostenbrugge,Ѷ; Ángel Chamorro,Ѷ; Hester Lingsma, PhD; Frank L.Silver,Ѷ; Geoffrey A.Donnan,Ѷ; Ashfaq Shuaib,Ѷ; Scott Brown, PhD; Bruce Stouch, PhD; Peter J.Mitchell,Ѷ; Antoni Davalos,Ѷ; Yvo B. W. E. M.Roos,Ѷ; Michael D.Hill,Ѷ, MS; for the HERMES Collaborators
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has multimedia
JAMA. 2016; 316(12):1279-1289. 10.1001/jama.2016.13647
This meta-analysis of trials comparing treatment of acute ischemic stroke with vs without endovascular thrombectomy characterizes the threshold time after which treatment is no longer beneficial.
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Ƶ Neurology
Images in Neurology
December 1, 2013
Edilberto Amorim,Ѷ; Brian T.Jankowitz,Ѷ; Tudor G.Jovin,Ѷ; Ashutosh P.Jadhav,Ѷ, PhD
Ƶ Neurol. 2013; 70(12):1584-1585. 10.1001/jamaneurol.2013.1515
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Ƶ Neurology
Images in Neurology
November 1, 2013
Ashutosh P.Jadhav,Ѷ, PhD; Nima Aghaebrahim,Ѷ; Brian T.Jankowitz,Ѷ; Tudor G.Jovin,Ѷ
Ƶ Neurol. 2013; 70(11):1452-1453. 10.1001/2013.jamaneurol.505
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Ƶ Neurology
Images in Neurology
July 1, 2013
Daniel Lai, MD; Tudor G. Jovin, MD; Ashutosh P. Jadhav, MD, PhD
Ƶ Neurol. 2013; 70(7):939-940. 10.1001/jamaneurol.2013.1949
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Ƶ Neurology
Images in Neurology
June 1, 2013
Ashutosh P. Jadhav, MD, PhD; Georgios Zenonos, MD; Misha Pless, MD; Tudor G. Jovin, MD; Lawrence Wechsler, MD
Ƶ Neurol. 2013; 70(6):800-800. 10.1001/jamaneurol.2013.1947