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  • Development and Validation of a Postprocedural Model to Predict Outcome After Endovascular Treatment for Ischemic Stroke

    Abstract Full Text
    Ƶ Neurol. 2023; 80(9):940-948. 10.1001/jamaneurol.2023.2392

    This prognostic study investigates the effectiveness of a prognostic tool to predict the functional outcome of individual patients after endovascular treatment for ischemic stroke.

  • Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial

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    Ƶ Neurol. 2023; 80(8):779-788. 10.1001/jamaneurol.2023.1660

    This randomized clinical trial investigates the safety and efficacy of ApTOLL as a neuroprotectant drug for patients with ischemic stroke when given in combination with endovascular treatment.

  • Effect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas: The RACECAT Randomized Clinical Trial

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    JAMA. 2022; 327(18):1782-1794. 10.1001/jama.2022.4404

    This randomized trial assesses the effect of transportation to a local stroke center vs directly to a thrombectomy-capable referral center on 90-day disability among patients with acute large-vessel occlusion stroke attended by emergency medical services in areas where the closest local stroke center was not capable of performing thrombectomy.

  • Noncontrast Computed Tomography vs Computed Tomography Perfusion or Magnetic Resonance Imaging Selection in Late Presentation of Stroke With Large-Vessel Occlusion

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    Ƶ Neurol. 2021; 79(1):22-31. 10.1001/jamaneurol.2021.4082

    This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.

  • Assessment of Optimal Patient Selection for Endovascular Thrombectomy Beyond 6 Hours After Symptom Onset: A Pooled Analysis of the AURORA Database

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    Ƶ Neurol. 2021; 78(9):1064-1071. 10.1001/jamaneurol.2021.2319

    This pooled analysis uses data from 6 randomized clinical trials to assess the potential benefits of endovascular thrombectomy among patients with ischemic stroke based on 3 baseline imaging profiles.

  • Healthy Life-Year Costs of Treatment Speed From Arrival to Endovascular Thrombectomy in Patients With Ischemic Stroke: A Meta-analysis of Individual Patient Data From 7 Randomized Clinical Trials

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    Ƶ Neurol. 2021; 78(6):709-717. 10.1001/jamaneurol.2021.1055

    This meta-analysis evaluates outcomes along the full health-related quality-of-life range associated with time to endovascular thrombectomy in patients with ischemic stroke.

  • Mediation of the Relationship Between Endovascular Therapy and Functional Outcome by Follow-up Infarct Volume in Patients With Acute Ischemic Stroke

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    Ƶ Neurol. 2019; 76(2):194-202. 10.1001/jamaneurol.2018.3661

    This pooled data analysis of 7 randomized clinical trials of thrombectomy for acute ischemic stroke examines whether follow-up infarct volume mediates the relationship between endovascular therapy and functional outcome in patients with acute ischemic stroke.

  • Association of Time From Stroke Onset to Groin Puncture With Quality of Reperfusion After Mechanical Thrombectomy: A Meta-analysis of Individual Patient Data From 7 Randomized Clinical Trials

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    Ƶ Neurol. 2019; 76(4):405-411. 10.1001/jamaneurol.2018.4510

    This meta-analysis of individual patient data from 7 randomized clinical trials analyzes the rate of reperfusion after endovascular thrombectomy started at different intervals after symptom onset in patients with acute ischemic stroke.

  • Monitored Anesthesia Care vs Intubation for Vertebrobasilar Stroke Endovascular Therapy

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    Ƶ Neurol. 2017; 74(6):704-709. 10.1001/jamaneurol.2017.0192

    This case-control study compares clinical and angiographic outcomes between monitored anesthesia care and general anesthesia in patients presenting with vertebrobasilar occlusion strokes.

  • Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis

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    JAMA. 2016; 316(12):1279-1289. 10.1001/jama.2016.13647

    This meta-analysis of trials comparing treatment of acute ischemic stroke with vs without endovascular thrombectomy characterizes the threshold time after which treatment is no longer beneficial.

  • Recovery From Ophthalmoplegia and Proptosis After Repair of Bilateral Carotid-Cavernous Sinus Fistulas

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    Ƶ Neurol. 2013; 70(12):1584-1585. 10.1001/jamaneurol.2013.1515
  • Cerebral Microbleeds in Lupus Anticoagulant-Hypoprothrombinemia Syndrome

    Abstract Full Text
    Ƶ Neurol. 2013; 70(11):1452-1453. 10.1001/2013.jamaneurol.505
  • Cortical Vein Air Emboli With Gyriform Infarcts

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    Ƶ Neurol. 2013; 70(7):939-940. 10.1001/jamaneurol.2013.1949
  • A Variant of the Anterior Opercular Syndrome With Supranuclear Gaze Palsy

    Abstract Full Text
    Ƶ Neurol. 2013; 70(6):800-800. 10.1001/jamaneurol.2013.1947