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This substudy of a randomized clinical trial investigates the effects of pitavastatin on noncalcified coronary artery plaque using coronary computed tomography angiography and on inflammatory biomarkers as potential mechanisms for major adverse cardiovascular event prevention.

This cohort study compares the risk factors and noninvasive testing outcomes of Black and White persons with stable chest pain.

This cohort study examines the prevalence of coronary artery disease (CAD) among adults with well-controlled HIV and low to moderate risk of atherosclerotic cardiovascular disease using computed tomography angiography and assessment of inflammation and immune activation biomarkers.

This cohort study examines the doses of cardiac substructure radiation associated with major cardiac adverse events and all-cause mortality in patients with locally advanced non–small cell lung cancer.

This economic evaluation determines whether anatomic approaches are cost-effective compared with functional tests for the assessment of low-risk stable chest pain.

This prespecified analysis of the PROMISE randomized clinical trial determines whether the prognostic utility of anatomic vs functional testing for coronary artery disease varies based on patient age.

This prognostic study develops and tests a convoluted neural network (CXR-risk) to predict long-term mortality from chest radiographs.

This nested observational cohort study seeks to determine whether high-risk plaque detected by coronary computed tomographic angiography was independently associated with major adverse cardiovascular events.

This community-based cohort study of Framingham Heart Study participants applies unsupervised machine learning to define the distribution and prognostic importance of computed tomography–based multiorgan phenotypes associated with adverse health outcomes.

This study examines the predictive ability of coronary artery calcium score vs age for incident atherosclerotic cardiovascular disease and how risk prediction changes by adding coronary artery calcium score and removing only age from prediction models.

This community-based study compares the relative accuracy of US Preventive Services Task Force and American College of Cardiology/American Heart Association recommendations in identifying African American individuals with subclinical and clinical atherosclerotic cardiovascular disease.

This secondary analysis of the PROMISE randomized clinical trial describes a risk tool developed to use only pretest clinical data to identify patients with chest pain with normal coronary arteries and no clinical events during follow-up.

This meta-analysis of data from 5 population-based cohort studies assesses the associations between coronary artery calcium (CAC) score and atherosclerotic cardiovascular disease (CVD) in low-risk women and the changes in risk discrimination when CAC score is added to traditional CVD risk factors.

This study evaluates the effects of newly initiated antiretroviral therapy (ART) on arterial inflammation and other immune/inflammatory indices in ART-naive patients with human immunodeficiency virus infection.

This study uses data from 4 population cohorts of people with and without chronic obstructive pulmonary disease to investigate associations between interstitial lung abnormalities (identified by computed tomography) and all-cause mortality.

This study uses Framingham cohort data to assess whether the 2013 American College of Cardiology/American Heart Association guidelines for cholesterol management improve identification of adults at higher risk of cardiovascular events compared with the 2004 Adult Treatment Panel III guidelines.