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  • JAMA Oncology Comment & Response
    April 11, 2024

    Local Immunoradiotherapy in Patients With Metastatic Soft-Tissue Sarcoma鈥擱eply

    Yongwoo David听Seo,听MD; Seth M.听Pollack,听MD
    Abstract Full Text
    online first
    JAMA Oncol. 2024; 10.1001/jamaoncol.2024.0311
  • JAMA Oncology Original Investigation
    October 12, 2023

    Toll-Like Receptor 4 Agonist Injection With Concurrent Radiotherapy in Patients With Metastatic Soft Tissue Sarcoma: A Phase 1 Nonrandomized Controlled Trial

    Yongwoo David听Seo,听MD; Hailing听Lu,听MD, PhD; Graeme听Black,听BS; Kimberly听Smythe,听BS; Yuexin听Yu,听PhD; Cynthia听Hsu,听BS; Juliana听Ng,听BS; Pedro听Hermida de Viveiros,听MD; E. Houston听Warren,听MD, PhD; Brett A.听Schroeder,听MD; Ryan B.听O鈥橫alley,听MD; Lee D.听Cranmer,听MD, PhD; Elizabeth T.听Loggers,听MD, PhD; Michael J.听Wagner,听MD; Lynn听Bonham,听PhD; Venu G.听Pillarisetty,听MD; Gabrielle听Kane,听MD; Peter听Berglund,听PhD; Frank J.听Hsu,听MD; Xinlei听Mi,听PhD; Borislav A.听Alexiev,听MD; Robert H.听Pierce,听MD; Stanley R.听Riddell,听MD; Robin L.听Jones,听MD; Jan听ter Meulen,听MD, PhD; Edward Y.听Kim,听MD; Seth M.听Pollack,听MD
    Abstract Full Text
    open access
    JAMA Oncol. 2023; 9(12):1660-1668. 10.1001/jamaoncol.2023.4015

    This nonrandomized controlled trial of patients with advanced soft tissue sarcoma analyzed the immunomodulatory effects of intratumoral glycopyranosyl lipid A in stable-emulsion formulation with concurrent radiotherapy.