Explore the latest in pathology and laboratory medicine, including AI applications to biopsy readings, diagnostic test interpretation, and more.
This cohort study examines the applicability of personalized colorectal cancer (CRC) screening with fecal-hemoglobin (f-Hb)-guided screening intervals to reduce the number of fecal immunological tests and colonoscopy, as well as determine if it demonstrates equivalent efficacy as universal biennial screening.
This post hoc analysis of PIONEER I and II randomized clinical trials assessed whether receiving adalimumab was associated with decreased hematologic abnormalities and increased clinical improvement in patients with hidradenitis suppurativa.
This cross-sectional study evaluates the information on a circulating tumor DNA test available to the public on popular internet resources.
This secondary analysis of a randomized clinical trial evaluates the temporal association between 72-hour hazard periods of exposure to red blood cell (RBC) transfusions and necrotizing enterocolitis among extremely low-birthweight infants randomized to higher or lower hemoglobin transfusion thresholds.
This cohort study examines the association of plasma leptin levels with the 2 key protein pathologies of Alzheimer disease, amyloid beta and tau deposition, among cognitively unimpaired older adults.
This essay describes the author’s experience of improved patient care and collaboration the day the the electronic medical records system went down.
This cohort study compares individuals with previous SARS-CoV-2 infection and SARS-CoV-2–naive individuals for their saliva and serum responses after infection and vaccination or vaccination alone.
This Viewpoint discusses the challenges involved with secondary health care data collection vs primary data collection and provides a list of suggested data checks before registration of a study protocol using secondary data.
This cross-sectional study investigates perioperative oxygen saturation differences in Black and White infants with single ventricles undergoing stage 1 palliation.
This cross-sectional study evaluates the association of preoperative circulating tumor HPV DNA levels with disease burden or adverse pathologic features among patients with HPV-associated oropharyngeal squamous cell carcinoma who have undergone primary transoral robotic surgery.
This diagnostic study compares the performance of tuberculin skin testing and interferon-γ release assays in predicting development of tuberculosis (TB) disease in the US.
A man in his 40s was referred for an 8-mm red, firm, mobile nodule with irregular red lacunae and vessels and an absence of septa. What is your diagnosis?
This diagnostic study evaluates the performance of a handheld mass spectrometry device used for in vivo and ex vivo molecular analysis during breast cancer operations to discriminate healthy breast tissue from invasive ductal carcinoma.
This economic evaluation investigates the cost-effectiveness of parathyroid cryopreservation and delayed autotransplantation as a treatment for permanent hypoparathyroidism as a result of thyroid/parathyroid surgery.
This randomized clinical trial evaluates the effectiveness of serum S100B measurement to reduce exposure to cranial computed tomographic scans among children admitted to the emergency department with minor head trauma.
This cohort study investigates whether there is a long-term association between the Veterans Affairs (VA) Patient-Aligned Cancer Team implementation and timely follow-up of abnormal diagnostic test results for 6 different cancers.
This randomized clinical trial evaluates a rapid syndromic polymerase chain reaction–based diagnostic test for lower respiratory tract infections in patients presenting to the emergency department.
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