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April 24, 2024
Original Investigation

Atrial Fibrillation Ablation in Heart Failure With Reduced vs Preserved Ejection Fraction: A Systematic Review and Meta-Analysis

Abstract Full Text
JAMA Cardiol. Published online April 24, 2024. doi:10.1001/jamacardio.2024.0675

This systematic review and meta-analysis investigates the efficacy of catheter ablation compared with rate or rhythm control among patients with atrial fibrillation and heart failure.

Research Letter

Reversals in the Decline of Heart Failure Mortality in the US, 1999 to 2021

Abstract Full Text
JAMA Cardiol. Published online April 24, 2024. doi:10.1001/jamacardio.2024.0615

This cohort study evaluates recent reversals in declines in cardiovascular mortality and whether they vary across sociodemographic categories.

Viewpoint

Fontan Junctional Rhythm—Innocent Bystander or Silent Killer?

Abstract Full Text
JAMA Cardiol. Published online April 24, 2024. doi:10.1001/jamacardio.2024.0689

This Viewpoint discusses the impact of sinus node dysfunction and escape junctional rhythm associated with the Fontan procedure on patient outcomes.

Editor's Note

Atrial Fibrillation Ablation in Heart Failure—More Data Are Needed

Abstract Full Text
JAMA Cardiol. Published online April 24, 2024. doi:10.1001/jamacardio.2024.0684
April 17, 2024
Original Investigation

Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial

Abstract Full Text
has audio
JAMA Cardiol. Published online April 17, 2024. doi:10.1001/jamacardio.2024.0520

This post hoc analysis of A Study to Evaluate the Corvia Medical Inc IASD System II to Reduce Elevated Left Atrial Pressure in Patients With Heart Failure (REDUCE LAP-HF II) randomized clinical trial evaluates the long-term effects of an atrial shunt device on cardiac structure and function in patients with heart failure and preserved or mildly reduced ejection fraction.

Extended Clopidogrel Monotherapy vs DAPT in Patients With Acute Coronary Syndromes at High Ischemic and Bleeding Risk: The OPT-BIRISK Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online April 17, 2024. doi:10.1001/jamacardio.2024.0534

This randomized clinical trial evaluates clopidogrel monotherapy vs dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions who are at high bleeding and ischemic risk.

Invited Commentary

Clopidogrel Monotherapy for Double-Risk Acute Coronary Syndrome

Abstract Full Text
JAMA Cardiol. Published online April 17, 2024. doi:10.1001/jamacardio.2024.0547
Cardiovascular Images

Man in His Sixth Decade of Life With Totally Occluded Abdominal Aorta (Leriche Syndrome)

Abstract Full Text
has active quiz
JAMA Cardiol. Published online April 17, 2024. doi:10.1001/jamacardio.2024.0530

This case report discusses a diagnosis of Leriche syndrome in a male patient with peripheral arterial disease, erectile dysfunction, and nonischemic cardiomyopathy.

April 10, 2024
Original Investigation

Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1

Abstract Full Text
JAMA Cardiol. Published online April 10, 2024. doi:10.1001/jamacardio.2024.0459

This cohort study investigates the association of clonal hematopoiesis of indeterminate potential with risk for atrial fibrillation.

April 7, 2024
Original Investigation

Plozasiran (ARO-APOC3) for Severe Hypertriglyceridemia: The SHASTA-2 Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online April 7, 2024. doi:10.1001/jamacardio.2024.0959

This randomized clinical trial assesses the safety and effectiveness of plozasiran, an investigational APOC3-targeted drug, in the reduction of serum triglyceride level in patients with severe hypertriglyceridemia.

Brief Report

Influenza Vaccine Immune Response in Patients With High-Risk Cardiovascular Disease: A Secondary Analysis of the INVESTED Randomized Clinical Trial

Abstract Full Text
open access
JAMA Cardiol. Published online April 7, 2024. doi:10.1001/jamacardio.2024.0468

This secondary analysis of a randomized clinical trial examines the antibody response to high-dose trivalent compared with standard-dose quadrivalent inactivated influenza vaccine in patients with a recent acute myocardial infarction or heart failure hospitalization.

April 6, 2024
Original Investigation

A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression

Abstract Full Text
JAMA Cardiol. Published online April 6, 2024. doi:10.1001/jamacardio.2024.0595

This cohort study explores whether a novel artificial intelligence (AI) video-based biomarker for aortic stenosis is associated with development and progression of aortic stenosis.

Antibiotic Prophylaxis and Infective Endocarditis Incidence Following Invasive Dental Procedures: A Systematic Review and Meta-Analysis

Abstract Full Text
JAMA Cardiol. Published online April 6, 2024. doi:10.1001/jamacardio.2024.0873

This systematic review and meta-analysis evaluates associations between antibiotic prophylaxis and infective endocarditis following invasive dental procedures.

April 3, 2024
Original Investigation

Intravascular Imaging–Guided Optimization of Complex Percutaneous Coronary Intervention by Sex: A Subgroup Analysis of the RENOVATE-COMPLEX-PCI Trial

Abstract Full Text
JAMA Cardiol. Published online April 3, 2024. doi:10.1001/jamacardio.2024.0291

This prespecified subanalysis of the RENOVATE-COMPLEX-PCI trial evaluates potential differences in outcomes with intravascular imaging–guided percutaneous coronary intervention of complex coronary artery lesions between women and men.

Brief Report

Risk of Cardiac Arrhythmias Among Climbers on Mount Everest

Abstract Full Text
JAMA Cardiol. Published online April 3, 2024. doi:10.1001/jamacardio.2024.0364

This cohort study examines data from climbers at Mount Everest to explore the incidence of tachyarrhythmias and bradyarrhythmias in healthy individuals at high altitudes.

Cardiovascular Images

Spontaneous Coronary Artery Dissection in a Healthy Man With Non–ST Elevation Myocardial Infarction

Abstract Full Text
has active quiz
JAMA Cardiol. Published online April 3, 2024. doi:10.1001/jamacardio.2024.0381

This case report discusses a diagnosis of spontaneous coronary artery dissection in an otherwise healthy man with non–ST elevation myocardial infarction.

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