Transgender people with cancer navigate a health care system not designed to meet their needs, which can profoundly affect their health. In a 2020 survey, 40% of transgender respondents had postponed or avoided recommended screenings due to discriminatory experiences.1 This response group included 18% of all respondents and 28% of people of color (included Asian, Black, Hispanic, and multiracial individuals as well as those identifying as 鈥渙ther, non-Hispanic鈥�) who had been refused care because of their gender identity or expression. Unfortunately, these disparities extend into oncology clinics. It is important for oncologists to recognize how these experiences contribute to disparities in cancer screening, timely diagnosis, and access to cancer treatment.