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´¡±è°ù¾±±ôÌý26, 2024

CDC: H5N1 Bird Flu Confirmed in Person Exposed to Cattle

JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6720

Highly pathogenic avian influenza A(H5N1), also known as H5N1 bird flu, has for the past few years. This March, US officials detected it in in several states. Later that month, a farm worker who was exposed to dairy cattle in Texas tested positive for H5N1 bird flu, the US Centers for Disease Control and Prevention (CDC) announced in a .

The person developed conjunctivitis and was treated with an influenza antiviral. The farm worker is the second person in the US with a confirmed infection; the first tested positive in 2022 in Colorado. Despite this recent human infection, the risk to the general public remains low, the CDC said.

Given the recent human infection, clinicians should in people with acute respiratory symptoms, including conjunctivitis, who have been in contact with birds, livestock, or other animals within 10 days before symptoms began.

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Published Online: April 26, 2024. doi:10.1001/jama.2024.6720

1 Comment for this article
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Importance of monitoring D type human influenza along with H5N1 avian influenza virus
takuma hayashi, MBBS, DMSci, GRMC, PhD | National Hospital Organization Kyoto Medical Center
From November 2021 to March 2022, highly pathogenic avian influenza (HPAI) type A (H5N1) viruses were detected in Denmark and Italy, and A type (H5N1) viruses were detected in the UK, South Africa, Australia, and South Korea. H5N2) virus was detected. In addition, A(H5N3) viruses have been detected in Japan, South Korea, the United States, France, and Italy, and A(H5N8) viruses have been detected in South Korea. Each type of avian influenza virus has been detected in domestic or wild birds. Additionally, between November 2021 and March 2022, wild birds and poultry infected with A type (H5N1) or A type (H5N8) viruses were found throughout Japan. The cause of the new influenza pandemic that occurred in 2009 was an outbreak of infectious diseases caused by the H1N1 subtype of the influenza A virus. The H1N1 virus was a zoonotic disease caused by a virus that was caused by the recombination of human influenza virus genes with avian influenza virus genes in pigs.

On April 23, 2024, the U.S. Food and Drug Administration (FDA) reported that pasteurized milk tested positive for H5N1 avian influenza. It is thought that the H5N1 avian influenza infection is spreading more widely among cattle than expected.

Humans can become infected with the H5N1 avian influenza virus through close contact with poultry infected with the H5N1 virus, or with poultry excrement, carcasses, or organs. In Japan, no humans have been confirmed to have developed symptoms after being infected with H5N1. However, in Japan, infection of cows with type D human influenza, which is different from type A human influenza virus, has been confirmed. In the future, viruses created by recombining the genes of the D type human influenza virus and the H5N1 avian influenza virus in cattle may cause zoonotic infections. Therefore, in order to prevent the emergence of pandemic viruses, it is necessary to monitor human influenza D type as well as H5N1 avian influenza virus.

We do not have potential conflicts of interest.

Dr. Takuma Hayashi, Dr. Ikuo Konishi
National Hospital Organization Kyoto Medical Center
CONFLICT OF INTEREST: None Reported
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