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May 7, 2024, Vol 331, No. 17, Pages 1431-1512

In This Issue of JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2024;331(17):e2318276. doi:10.1001/jama.2023.18276
  • Audio: Prostate Cancer Screening, Clinical Outcomes for Cancer Drugs Granted Accelerated Approval, Lupus Review, and more
Original Investigation

Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial

Richard M. Martin, BM, BS, PhD; Emma L. Turner, PhD; Grace J. Young, MSc; et al.
Abstract Full Text
has active quiz has audio
JAMA. 2024;331(17):1460-1470. doi:10.1001/jama.2024.4011

This secondary analysis of a randomized clinical trial assesses whether screening for prostate-specific antigen reduces prostate cancer mortality at 15-year follow-up.

  • Audio: The Evolution of Screening Tools for Prostate Cancer

Clinical Benefit and Regulatory Outcomes of Cancer Drugs Receiving Accelerated Approval

Ian T. T. Liu, MD, JD, MPH, MS; Aaron S. Kesselheim, MD, JD, MPH; Edward R. Scheffer Cliff, MBBS, MPH
Abstract Full Text
JAMA. 2024;331(17):1471-1479. doi:10.1001/jama.2024.2396

This study aims to determine whether cancer drugs granted accelerated approval from the US Food and Drug Administration ultimately demonstrate clinical benefit and to evaluate the basis of conversion to regular approval.

Preliminary Communication

Prostate Cancer Screening With PSA, Kallikrein Panel, and MRI: The ProScreen Randomized Trial

Anssi Auvinen, MD, PhD; Teuvo L. J. Tammela, MD, PhD; Tuomas Mirtti, MD, PhD; et al.
Abstract Full Text
has audio
JAMA. 2024;331(17):1452-1459. doi:10.1001/jama.2024.3841

This preliminary descriptive report compares the detection rates of high-grade and low-grade prostate cancer in men invited for prostate cancer screening vs those of the control group not offered screening.

  • Audio: The Evolution of Screening Tools for Prostate Cancer
Research Letter

Cardiac Function Before Sepsis and Clinical Outcomes

Stuthi Iyer, MPH; Jason N. Kennedy, MS; Jacob C. Jentzer, MD; et al.
Abstract Full Text
JAMA. 2024;331(17):1496-1499. doi:10.1001/jama.2024.3917

This cohort study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospitalization outcomes and mortality.

Intravascular Microaxial Left Ventricular Assist Device Manufacturer Payments to Cardiologists and Use of Devices

Sanket S. Dhruva, MD, MHS; Joseph S. Ross, MD, MHS; Michael A. Steinman, MD; et al.
Abstract Full Text
JAMA. 2024;331(17):1499-1501. doi:10.1001/jama.2024.4682

This study examines whether payments from a left ventricular assist device manufacturer to cardiologists performing percutaneous coronary intervention were associated with any use of the devices.

Viewpoint

Health and the 2024 US Election

US Supreme Court Limits on the Power of US Health Agencies

Daniel G. Aaron, MD, JD; Avery E. Emery, BS
Abstract Full Text
JAMA. 2024;331(17):1441-1442. doi:10.1001/jama.2024.3723

This Viewpoint describes how the overturning of Chevron deference would shift the ability to make policy decisions about public health and the environment from administrative agencies to the courts.

Health and the 2024 US Election

Implications for Public Health Regulation if Chevron Deference Is Overturned

Sahil Agrawal, MD, PhD; Joseph S. Ross, MD, MHS; Reshma Ramachandran, MD, MPP, MHS
Abstract Full Text
JAMA. 2024;331(17):1443-1444. doi:10.1001/jama.2024.3654

This Viewpoint describes implications for medicine and public health if the US Supreme Court decides to overturn or narrow Chevron deference.

Data Checks Before Registering Study Protocols for Health Care Database Analyses

Shirley V. Wang, PhD; Sebastian Schneeweiss, MD, ScD
Abstract Full Text
JAMA. 2024;331(17):1445-1446. doi:10.1001/jama.2024.2988

This Viewpoint discusses the challenges involved with secondary health care data collection vs primary data collection and provides a list of suggested data checks before registration of a study protocol using secondary data.

A Piece of My Mind

Good Enough

Lauren Rissman, MD
Abstract Full Text
free access
JAMA. 2024;331(17):1447. doi:10.1001/jama.2024.2937

In this narrative medicine essay, a pediatric critical care physician mulls a discussion about a patient鈥檚 status with a male colleague in front of her all-female medical team, a discussion that led her to question herself until she concludes that she can鈥檛 be all things to all people at all times.

Editorial

A Pragmatic Approach to Prostate Cancer Screening

Jeffrey J. Tosoian, MD, MPH; David F. Penson, MD, MPH; Arul M. Chinnaiyan, MD, PhD
Abstract Full Text
has audio
JAMA. 2024;331(17):1448-1450. doi:10.1001/jama.2024.4089
  • Audio: The Evolution of Screening Tools for Prostate Cancer

Introducing the JAMA Summit

Kirsten Bibbins-Domingo, PhD, MD, MAS; Derek C. Angus, MD, MPH; Hannah Park; et al.
Abstract Full Text
free access
JAMA. 2024;331(17):1451. doi:10.1001/jama.2024.5570
Review

Systemic Lupus Erythematosus: A Review

Caroline H. Siegel, MD, MS; Lisa R. Sammaritano, MD
Abstract Full Text
has active quiz has audio
JAMA. 2024;331(17):1480-1491. doi:10.1001/jama.2024.2315

This review summarizes current evidence regarding the diagnosis, treatment, and prognosis of systemic lupus erythematosus.

  • Audio: Diagnosis and Treatment of Systemic Lupus Erythematosus
JAMA Insights

Women's Health

Uterine Fibroids

Erica E. Marsh, MD, MSCI; Ganesa Wegienka, PhD; David R. Williams, PhD, MPH
Abstract Full Text
has active quiz
JAMA. 2024;331(17):1492-1493. doi:10.1001/jama.2024.0447

This JAMA Insights in the Women鈥檚 Health series discusses the incidence, diagnosis, and treatment of uterine fibroids.

JAMA Diagnostic Test Interpretation

Tilt Table Testing

William P. Cheshire, MD; Daniel V. Dudenkov, MD; Bala Munipalli, MD
Abstract Full Text
has active quiz
JAMA. 2024;331(17):1494-1495. doi:10.1001/jama.2024.0004

This Diagnostic Test Interpretation uses a patient case to illustrate tilt table testing, useful for evaluating patients with syncope of unknown cause or postural orthostatic tachycardia syndrome (POTS).

Medical News & Perspectives

Produce Prescriptions Sound Good, but Data to Support Them Are Lacking鈥擳hat Could Soon Change

Maryn McKenna
Abstract Full Text
free access has audio
JAMA. 2024;331(17):1433-1436. doi:10.1001/jama.2024.2251

This Medical News article discusses research initiatives to support produce prescriptions and other 鈥渇ood is medicine鈥� nutrition programs in health care settings.

  • Audio: April 26, 2024, Medical News Summary

Quick Uptakes

Could 鈥淓mpathetic Refutation鈥� Help Clinicians Sway Vaccine Skeptics?

Samantha Anderer
Abstract Full Text
free access
JAMA. 2024;331(17):1437-1438. doi:10.1001/jama.2024.4493

This Medical News article discusses an intervention that uses empathy to address vaccine hesitancy in the clinic.

Medical News in Brief

COVID-19 Vaccination Linked With Lower Risk of Cardiac Problems

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1439. doi:10.1001/jama.2024.5152

Measles Outbreaks in US and Abroad Prompt CDC Vaccination Alert

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1439. doi:10.1001/jama.2024.5153

FDA Okays First Drug for Scarring From Fatty Liver Disease

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1439. doi:10.1001/jama.2024.5154

Safety Concerns Put a Stop to Maternal RSV Vaccine Study

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1439. doi:10.1001/jama.2024.5155

Trials Will Evaluate Treatments for Long COVID Nervous System Problems

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1439-1440. doi:10.1001/jama.2024.5156

AI-Drafted Responses to Patients Reduced Clinician Burnout

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1440. doi:10.1001/jama.2024.5157

Study Examines Intermittent Fasting and Cardiovascular Mortality

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1440. doi:10.1001/jama.2024.5158

More Than 1 in 10 US Children Diagnosed With ADHD

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1440. doi:10.1001/jama.2024.5159

Neurological Conditions Are Leading Cause of Disability Worldwide

Emily Harris
Abstract Full Text
free access
JAMA. 2024;331(17):1440. doi:10.1001/jama.2024.5160
Poetry and Medicine

Sternotomy

Mitch Browne
Abstract Full Text
free access
JAMA. 2024;331(17):1507. doi:10.1001/jama.2024.0496
JAMA Revisited

Medicine and Meteorology

Abstract Full Text
free access
JAMA. 2024;331(17):1508. doi:10.1001/jama.2023.18277
JAMA Patient Page

Flat Head Syndrome in Infants

Geisel R. Collazo, MD; Maria Isabel Angulo, MD
Abstract Full Text
free access
JAMA. 2024;331(17):1512. doi:10.1001/jama.2023.26048

This JAMA Patient Page describes the types of flat head syndrome and its prevention and treatment.

Comment & Response

Metformin Plus Insulin for Preexisting Diabetes or Gestational Diabetes in Pregnancy

Fariba Pourkarim, PharmD; Taher Entezari-Maleki, PharmD
Abstract Full Text
JAMA. 2024;331(17):1502. doi:10.1001/jama.2024.1380

Metformin Plus Insulin for Preexisting Diabetes or Gestational Diabetes in Pregnancy鈥擱eply

Kim A. Boggess, MD; MOMPOD Study PIs
Abstract Full Text
JAMA. 2024;331(17):1502. doi:10.1001/jama.2024.1383

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Patrick Schober, MD, PhD, MMedStat; Stephan Alexander Loer, MD, PhD, MSc; Lothar Andreas Schwarte, MD, PhD, MBA
Abstract Full Text
JAMA. 2024;331(17):1502-1503. doi:10.1001/jama.2024.1417

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Cheng-Han Chiang, MD; Tou-Yuan Tsai, MD; Yi-Kung Lee, MD, MPH
Abstract Full Text
JAMA. 2024;331(17):1503-1504. doi:10.1001/jama.2024.1429

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Frédéric M. Jacobs, MD, MSc
Abstract Full Text
JAMA. 2024;331(17):1504. doi:10.1001/jama.2024.1426

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Romain Jouffroy, MD, PhD; Raquel Tena, MD; Benoît Vivien, MD, PhD
Abstract Full Text
JAMA. 2024;331(17):1504. doi:10.1001/jama.2024.1423

Noninvasive Airway Management of Comatose Patients With Acute Poisoning鈥擱eply

Yonathan Freund, MD, PhD; Ben Bloom, MD
Abstract Full Text
JAMA. 2024;331(17):1505. doi:10.1001/jama.2024.1432
Correction

Consortium Authors and Nonauthor Collaborators Added

Abstract Full Text
free access
JAMA. 2024;331(17):1505. doi:10.1001/jama.2024.2984

Error in Conflict of Interest Disclosures

Abstract Full Text
free access
JAMA. 2024;331(17):1505. doi:10.1001/jama.2024.5360
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2024;331(17):1431-1432. doi:10.1001/jama.2023.18275

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Prevalence of Cardiovascular-Kidney-Metabolic Syndrome Stages in US Adults, 2011-2020
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A 3-Year-Old With Gingival Hemorrhage and Musculoskeletal Pain
JAMA Clinical Challenge | May 8, 2024
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