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2024
April March
April 26, 2024
Editor's Note

Introducing JAMA Data Brief

Jennifer Abbasi, BA; Karen Bucher, MA, CMI; Andy Rekito, MS; et al.
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.7960
News From the 榴莲视频 Network

Researchers See Hope in Symptom-Guided Exercise for Long COVID With Postexertional Malaise

Anna Bock
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.7255

This Medical News story discusses a clinical trial that tested symptom-guided exercise for patients with long COVID and postexertional malaise.

JAMA Data Brief

False Health Claims Abound, but Physicians Are Still the Most Trusted Source for Health Information

Melissa Suran, PhD, MSJ; Karen Bucher, MA, CMI
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6837

This Medical News article discusses a KFF poll about the public鈥檚 exposure to and beliefs about inaccurate health information, as well as media use and trust in sources.

  • Editor's Note
    Introducing JAMA Data Brief
    Jennifer Abbasi, BA; Karen Bucher, MA, CMI; Andy Rekito, MS; Stephen Schenkel, MD, MPP; Annette Flanagin, RN, MA
    JAMA
Medical News in Brief

US Updates Race, Ethnicity Categories for First Time Since 1997

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6713

CDC Warns of Surge in Meningococcal Disease in US

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6714

New Rules Require Explicit Consent for Students to Perform Sensitive Exams

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6715

Dengue Cases Surge in Latin America and Caribbean

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6716

Abnormal Glucose, Triglycerides Linked to Later Psychiatric Conditions

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6717

Limited Pregnancy Weight Gain for People With Obesity Might Be Safe

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6718

Climbers at High Altitudes at Risk of Heart Rhythm Abnormalities

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6719

CDC: H5N1 Bird Flu Confirmed in Person Exposed to Cattle

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6720

WHO Launches Broad Coronavirus Surveillance Network

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 26, 2024. doi:10.1001/jama.2024.6724
April 25, 2024
Original Investigation

Disparities in Mortality by Sexual Orientation in a Large, Prospective Cohort of Female Nurses

Sarah McKetta, MD, PhD; Tabor Hoatson, MPH; Landon D. Hughes, PhD; et al.
Abstract Full Text
has audio
JAMA. Published online April 25, 2024. doi:10.1001/jama.2024.4459

This prospective cohort study compares the differences in time to mortality across sexual orientation in female nurses participating in the Nurses鈥� Health Study II.

  • Audio: Examining Mortality Disparities by Sexual Orientation Among Female Nurses
A Piece of My Mind

In Praise of Hospice

James R. Nicholas, MD
Abstract Full Text
free access
JAMA. Published online April 25, 2024. doi:10.1001/jama.2024.3335

In this narrative medicine essay, a retired physician describes the kindness, companionship, and skill of the hospice workers who helped his wife and him prepare for her death.

JAMA Insights

APOL1-Mediated Kidney Disease

Timothy Hopper, MD; Opeyemi A. Olabisi, MD, PhD
Abstract Full Text
has active quiz
JAMA. Published online April 25, 2024. doi:10.1001/jama.2024.2667

This JAMA Insights reviews the origin of APOL1 high-risk genetic variants, defines APOL1-mediated kidney disease, and discusses recommendations for screening and management.

JAMA Revisited

Rehabilitation

Abstract Full Text
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JAMA. Published online April 25, 2024. doi:10.1001/jama.2023.18291
JAMA Patient Page

What Is Autism Spectrum Disorder?

Rebecca Voelker, MSJ
Abstract Full Text
free access
JAMA. Published online April 25, 2024. doi:10.1001/jama.2024.3041

This JAMA Patient Page describes autism spectrum disorder (ASD) and its signs and symptoms, diagnosis, and therapy options.

Comment & Response

US Breast Cancer Mortality

Ismail Jatoi, MD, PhD
Abstract Full Text
JAMA. Published online April 25, 2024. doi:10.1001/jama.2024.5479

US Breast Cancer Mortality鈥擱eply

Jennifer L. Caswell-Jin, MD; Allison W. Kurian, MD, MSc; Sylvia K. Plevritis, PhD
Abstract Full Text
JAMA. Published online April 25, 2024. doi:10.1001/jama.2024.5482
April 24, 2024
Original Investigation

Neurodevelopmental Outcomes After Late Preterm Antenatal Corticosteroids: The ALPS Follow-Up Study

Cynthia Gyamfi-Bannerman, MD, MS; Rebecca G. Clifton, PhD; Alan T. N. Tita, MD, PhD; et al.
Abstract Full Text
has active quiz
JAMA. Published online April 24, 2024. doi:10.1001/jama.2024.4303

This prospective follow-up study of a randomized clinical trial evaluates whether antenatal corticosteroids administered to birthing parents at risk of late preterm delivery were associated with adverse neurodevelopmental effects on their offspring.

Research Letter

Characteristics of X (Formerly Twitter) Community Notes Addressing COVID-19 Vaccine Misinformation

Matthew R. Allen, BS; Nimit Desai, BS; Aiden Namazi; et al.
Abstract Full Text
JAMA. Published online April 24, 2024. doi:10.1001/jama.2024.4800

This study evaluated the topics, accuracy, and credibility of X (formerly Twitter) Community Notes addressing COVID-19 vaccination.

Viewpoint

Is Myocardial Infarction Overdiagnosed?

Cian P. McCarthy, MB, BCh, BAO, SM; Jason H. Wasfy, MD, MPhil; James L. Januzzi Jr, MD
Abstract Full Text
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JAMA. Published online April 24, 2024. doi:10.1001/jama.2024.5235

This Viewpoint examines whether overdiagnosis rather than underdiagnosis may now be the dominant form of myocardial infarction misdiagnosis.

Editorial

Late Preterm Corticosteroids Exposure and Neurodevelopmental Outcomes

Alex C. Vidaeff, MD, MPH; Elizabeth Asztalos, MD, MSc
Abstract Full Text
JAMA. Published online April 24, 2024. doi:10.1001/jama.2024.2228
JAMA Clinical Guidelines Synopsis

Lower Gastrointestinal Hemorrhage

Hira Imran, MD; Jason T. Alexander, MD; Christopher D. Jackson, MD
Abstract Full Text
has active quiz
JAMA. Published online April 24, 2024. doi:10.1001/jama.2023.25841

This JAMA Clinical Guidelines Synopsis summarizes the 2023 American College of Gastroenterology guidelines on management of patients with acute lower gastrointestinal bleeding.

Poetry and Medicine

Toward the End of My Dad鈥檚 Life We Go Back to Arguing, and Soon After He Dies, I Break My Elbow

Jessica Greenbaum, LMSW
Abstract Full Text
free access
JAMA. Published online April 24, 2024. doi:10.1001/jama.2024.2626
Comment & Response

The Diagnosis of Cancer After Recent Weight Loss

Cheng-Hsien Hung, BS; Li-Yu Lu, MD; Yen-Yu Hsieh, MS
Abstract Full Text
JAMA. Published online April 24, 2024. doi:10.1001/jama.2024.5416

The Diagnosis of Cancer After Recent Weight Loss鈥擱eply

Qiao-Li Wang, MD, PhD; Chen Yuan, ScD; Brian M. Wolpin, MD, MPH
Abstract Full Text
JAMA. Published online April 24, 2024. doi:10.1001/jama.2024.5419
April 22, 2024
Original Investigation

Associations Between Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments

Joshua D. Wallach, PhD, MS; Samuel Yoon, BS, BA; Harry Doernberg, MM; et al.
Abstract Full Text
JAMA. Published online April 22, 2024. doi:10.1001/jama.2024.4175

This study examines the strength of association between surrogate markers used as primary end points in clinical trials to support FDA approval of drugs treating nononcologic chronic diseases and clinical outcomes.

Research Letter

Preoperative GLP-1 Receptor Agonist Use and Risk of Postoperative Respiratory Complications

Anjali A. Dixit, MD, MPH; Brian T. Bateman, MD, MS; Mary T. Hawn, MD, MPH; et al.
Abstract Full Text
JAMA. Published online April 22, 2024. doi:10.1001/jama.2024.5003

This cohort study evaluates the risk of postoperative respiratory complications among patients with diabetes undergoing surgery who had vs those who had not a prescription fill for glucagon-like peptide 1 receptor agonists.

Viewpoint

Health and the 2024 US Election

The Overdose Crisis in the 2024 Election鈥擯olitical Fights and Practical Problems

Brendan Saloner, PhD
Abstract Full Text
free access
JAMA. Published online April 22, 2024. doi:10.1001/jama.2024.4997

This Viewpoint discusses the 2024 presidential election in the context of the addiction and overdose crisis in the US, which has been a unifying challenge and a source of major ideological division in US politics.

Review

Interstitial Lung Disease: A Review

Toby M. Maher, MD, MSc, PhD
Abstract Full Text
has active quiz has audio
JAMA. Published online April 22, 2024. doi:10.1001/jama.2024.3669

This review summarizes current evidence regarding the diagnosis and treatment of interstitial lung disease.

  • Audio: Diagnosis and Treatment of Interstitial Lung Disease
Comment & Response

Measuring Equity in Readmission as an Assessment of Hospital Performance

Robert J. Gallo, MD; Christine Santiago, MD, MPH
Abstract Full Text
JAMA. Published online April 22, 2024. doi:10.1001/jama.2024.4351

Measuring Equity in Readmission as an Assessment of Hospital Performance鈥擱eply

Himali Weerahandi, MD, MPH; Katherine A. Nash, MD, MHS; Susannah M. Bernheim, MD, MHS
Abstract Full Text
JAMA. Published online April 22, 2024. doi:10.1001/jama.2024.4354
April 19, 2024
Original Investigation

Stewardship Prompts to Improve Antibiotic Selection for Pneumonia: The INSPIRE Randomized Clinical Trial

Shruti K. Gohil, MD, MPH; Edward Septimus, MD; Ken Kleinman, ScD; et al.
Abstract Full Text
has audio
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.6248

This clinical trial examines the effect of an antibiotic stewardship bundle (education, feedback, and real-time multidrug-resistant organism risk-based CPOE prompts) vs routine stewardship on antibiotic selection during the first 3 hospital days in adults with pneumonia.

  • Audio: Stewardship Prompts to Improve Antibiotic Selection for Pneumonia and Urinary Tract Infection

Stewardship Prompts to Improve Antibiotic Selection for Urinary Tract Infection: The INSPIRE Randomized Clinical Trial

Shruti K. Gohil, MD, MPH; Edward Septimus, MD; Ken Kleinman, ScD; et al.
Abstract Full Text
has audio
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.6259

This clinical trial evaluates whether computerized provider order entry prompts providing patient- and pathogen-specific multidrug-resistant organism risk estimates could reduce use of empiric extended-spectrum antibiotics for treatment of urinary tract infections.

  • Audio: Stewardship Prompts to Improve Antibiotic Selection for Pneumonia and Urinary Tract Infection
Editorial

Harnessing the Electronic Health Record to Improve Empiric Antibiotic Prescribing

Anurag N. Malani, MD; Preeti N. Malani, MD, MSJ
Abstract Full Text
has audio
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.6554
  • Audio: Stewardship Prompts to Improve Antibiotic Selection for Pneumonia and Urinary Tract Infection
Medical News & Perspectives

Could GLP-1 Receptor Agonists like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions?

Rita Rubin, MA
Abstract Full Text
free access has audio
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.1017

This Medical News story examines other potential uses of GLP-1 receptor agonists, the popular type 2 diabetes and weight-loss drugs.

  • Audio: April 26, 2024, Medical News Summary

Clinical Highlights From the American College of Cardiology鈥檚 2024 Scientific Session

Jennifer Abbasi
Abstract Full Text
free access has audio
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.6214

This Medical News article is an interview with Douglas Drachman, MD, an interventional cardiologist and chair of the American College of Cardiology鈥檚 annual meeting.

  • Audio: Highlights From the American College of Cardiology鈥檚 2024 Scientific Session
Medical News in Brief

Study: Roughly 1 in 8 Patients Wrongly Diagnosed With Pneumonia

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5920

People With Genetic Risk of Obesity Need More Exercise to Mitigate It

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5921

Type of Prenatal Antiseizure Drug Matters for Children鈥檚 Autism Risk

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5922

Use of Progestogen Tied to Higher Chance of Benign Brain Tumor

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5923

Loneliness Tied to Worse Physical, Mental Health Among Older Adults

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5924

Even Low Levels of Albumin in Urine Tied to Worsened Kidney Disease

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5925

Study: Younger Deaths Driving Maternal Mortality Increase

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5926

Heart Disease Outcomes Improve After Mental Health Treatments

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5927

Bacterial Subspecies Linked With Aggressive Colorectal Cancer Tumors

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.5928
April 18, 2024
A Piece of My Mind

鈥淭he Patient鈥�

Katie A. Thure, MPH
Abstract Full Text
free access
JAMA. Published online April 18, 2024. doi:10.1001/jama.2024.3082

When a resident announced that 鈥渢he patient has no chance of surviving,鈥� a medical student, in this narrative medicine essay, has pondered for years how her mother could have been so reduced and advocates using patients鈥� names when summarizing their conditions.

JAMA Revisited

The Promise of a Longer Lifetime

Abstract Full Text
free access
JAMA. Published online April 18, 2024. doi:10.1001/jama.2023.18284
JAMA Patient Page

What Is Hepatitis D Infection?

Rebecca Voelker, MSJ
Abstract Full Text
free access
JAMA. Published online April 18, 2024. doi:10.1001/jama.2024.1317

This JAMA Patient Page describes hepatitis D infection and its risk factors, outcomes of acute and chronic infection, diagnosis, treatment, and prevention.

Comment & Response

Estrogen-Only Hormone Therapy and Dementia

Sarah Glynne, MBBS, MSc
Abstract Full Text
JAMA. Published online April 18, 2024. doi:10.1001/jama.2024.4071

Estrogen-Only Hormone Therapy and Dementia

Madeline Wood Alexander, BA; Gillian Einstein, PhD; Jennifer S. Rabin, PhD, CPsych
Abstract Full Text
JAMA. Published online April 18, 2024. doi:10.1001/jama.2024.4074

Estrogen-Only Hormone Therapy and Dementia鈥擱eply

Nelsan Pourhadi, MD; Lina S. Mørch, PhD; Amani Meaidi, PhD
Abstract Full Text
JAMA. Published online April 18, 2024. doi:10.1001/jama.2024.4077
April 17, 2024
Research Letter

Outcomes of the Main Residency Match for Applicants With Disability

Mytien Nguyen, MS; Lisa M. Meeks, PhD; Zoie C. Sheets, MD, MPH; et al.
Abstract Full Text
JAMA. Published online April 17, 2024. doi:10.1001/jama.2024.5000

This cohort study assesses match rates of US applicants with and without disability into specialty residence programs.

Viewpoint

Climate Change and Health

Accelerating Climate Action Through Academic Health Systems: Leadership鈥檚 Call to Duty

A. Eugene Washington, MD, MSc; William T. Mallon, EdD; Johnese Spisso, RN, MPA
Abstract Full Text
free access has audio
JAMA. Published online April 17, 2024. doi:10.1001/jama.2024.4967

This Viewpoint makes the case for academic health systems to lead the way on climate change action in the US, including planning to reduce greenhouse gas emissions, educating current and future clinicians, and communicating with their patients and communities.

  • Audio: Advancing Climate Action Through Academic Health Systems
JAMA Clinical Challenge

A Patient With Type 1 Diabetes and Acute Rhinosinusitis

Francisco J. Machiavello Roman, MD; Marwan M. Azar, MD; Paul A. Trubin, MD
Abstract Full Text
has active quiz
JAMA. Published online April 17, 2024. doi:10.1001/jama.2024.0642

A 41-year-old with type 1 diabetes had generalized weakness, muffled voice, and slurred speech. Neck computed tomography showed soft-tissue gas in the nasopharynx and prevertebral fascia; examination of sinus mucosal samples identified numerous broad, nonseptate right-angled hyphae and fruiting bodies. What is the diagnosis and what would you do next?

Editor's Note

Understatement in Poetry (Quieter Than an MRI)

Rafael Campo, MD, MA
Abstract Full Text
free access
JAMA. Published online April 17, 2024. doi:10.1001/jama.2024.2410
Poetry and Medicine

Open MRI

Jennifer Poteet
Abstract Full Text
free access
JAMA. Published online April 17, 2024. doi:10.1001/jama.2024.2344
Comment & Response

Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity

Yifan Xiao, BS; Jiahao Meng, BS; Shuguang Gao, MD
Abstract Full Text
JAMA. Published online April 17, 2024. doi:10.1001/jama.2024.2600

Tirzepatide for Maintenance of Weight Reduction in Adults with Obesity鈥擱eply

Louis J. Aronne, MD; SURMOUNT-4 Investigators
Abstract Full Text
JAMA. Published online April 17, 2024. doi:10.1001/jama.2024.2603
April 15, 2024
Original Investigation

Serious Bleeding in Patients With Atrial Fibrillation Using Diltiazem With Apixaban or Rivaroxaban

Wayne A. Ray, PhD; Cecilia P. Chung, MD, MPH; C. Michael Stein, MB, ChB; et al.
Abstract Full Text
has active quiz
JAMA. Published online April 15, 2024. doi:10.1001/jama.2024.3867

This cohort study assesses the association of diltiazem with risk of serious bleeding compared with metoprolol in older adults with atrial fibrillation receiving apixaban or rivaroxaban.

Research Letter

Leave of Absence and Medical Student Placement Into Graduate Medical Education by Race and Ethnicity

Mytien Nguyen, MS; Hyacinth R. C. Mason, PhD, MPH; Regina Russell, PhD, MA, MEd; et al.
Abstract Full Text
JAMA. Published online April 15, 2024. doi:10.1001/jama.2024.4797

This study examines the association between taking a leave of absence from medical school and placement into graduate medical education (GME) by race and ethnicity.

Viewpoint

Protecting Privacy of Pregnant and LGBTQ+ Research Participants

Ellen Wright Clayton, MD, JD; Harris T. Bland, MBA, MPH; Kathleen F. Mittendorf, PhD
Abstract Full Text
free access
JAMA. Published online April 15, 2024. doi:10.1001/jama.2024.4837

This Viewpoint summarizes existing federal regulations aimed at protecting research data, describes the challenges of enforcing these regulations, and discusses how evolving privacy technologies could be used to reduce health disparities and advance health equity among pregnant and LGBTQ+ research participants.

The Rational Clinical Examination

Does This Infant Have a Dislocated Hip?The Rational Clinical Examination Systematic Review

Abhinav Singh, BMBS, MSc; Ryckie George Wade, MBBS, PhD; David Metcalfe, MBChB, PhD; et al.
Abstract Full Text
has active quiz has multimedia has audio
JAMA. Published online April 15, 2024. doi:10.1001/jama.2024.2404

This Rational Clinical Examination systematic review summarizes studies that examined the diagnostic accuracy of clinical examination in determining dislocated hips in infants.

  • Video: Examining for a Dislocated Hip in Infants
  • Audio: Clinical Diagnosis of Dislocated Hips in Newborns
Comment & Response

Improving Medical Communication

LaKesha N. Anderson, PhD, CPD; Christy J. W. Ledford, PhD
Abstract Full Text
JAMA. Published online April 15, 2024. doi:10.1001/jama.2024.2590

Improving Medical Communication鈥擱eply

Anne R. Cappola, MD, ScM; Karthika S. Cohen, MS, MA
Abstract Full Text
JAMA. Published online April 15, 2024. doi:10.1001/jama.2024.2593
April 12, 2024
Original Investigation

Non鈥揌igh-Density Lipoprotein Cholesterol Levels From Childhood to Adulthood and Cardiovascular Disease Events

Feitong Wu, PhD; David R. Jacobs Jr, PhD; Stephen R. Daniels, MD, PhD; et al.
Abstract Full Text
has active quiz
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.4819

This study of individual participant data from 6 pooled cohorts assesses whether resolution of elevated childhood non鈥揾igh-density lipoprotein cholesterol (non鈥揌DL-C) by adulthood is associated with reduced risk of clinical cardiovascular disease (CVD) events.

Medical News & Perspectives

Produce Prescriptions Sound Good, but Data to Support Them Is Lacking鈥擳hat Could Soon Change

Maryn McKenna
Abstract Full Text
free access has audio
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.2251

This Medical News article discusses research initiatives to support produce prescriptions and other 鈥渇ood is medicine鈥� nutrition programs in health care settings.

  • Audio: April 26, 2024, Medical News Summary

Quick Uptakes

Could 鈥淓mpathetic Refutation鈥� Help Clinicians Sway Vaccine Skeptics?

Samantha Anderer
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.4493

This Medical News article discusses an intervention that uses empathy to address vaccine hesitancy in the clinic.

Medical News in Brief

COVID-19 Vaccination Linked With Lower Risk of Cardiac Problems

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5152

Measles Outbreaks in US and Abroad Prompt CDC Vaccination Alert

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5153

FDA Okays First Drug for Scarring From Fatty Liver Disease

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5154

Safety Concerns Put a Stop to Maternal RSV Vaccine Study

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5155

Trials Will Evaluate Treatments for Long COVID Nervous System Problems

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5156

AI-Drafted Responses to Patients Reduced Clinician Burnout

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5157

Study Examines Intermittent Fasting and Cardiovascular Mortality

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5158

More Than 1 in 10 US Children Diagnosed With ADHD

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5159

Neurological Conditions Are Leading Cause of Disability Worldwide

Emily Harris
Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.5160
Correction

Incorrect Text

Abstract Full Text
free access
JAMA. Published online April 12, 2024. doi:10.1001/jama.2024.6493
April 11, 2024
Viewpoint

Assessing the Real-World Effectiveness of Immunizations for Respiratory Syncytial Virus

Fatimah S. Dawood, MD; Amanda B. Payne, PhD; Meredith L. McMorrow, MD, MPH
Abstract Full Text
free access
JAMA. Published online April 11, 2024. doi:10.1001/jama.2024.5859

This Viewpoint discusses recommendations from the US Centers for Disease Control and Prevention for newly licensed immunizations for respiratory syncytial virus in infants, children with high-risk conditions, and older adults.

A Piece of My Mind

Good Enough

Lauren Rissman, MD
Abstract Full Text
free access
JAMA. Published online April 11, 2024. doi:10.1001/jama.2024.2937

In this narrative medicine essay, a pediatric critical care physician mulls a discussion about a patient鈥檚 status with a male colleague in front of her all-female medical team, a discussion that led her to question herself until she concludes that she can鈥檛 be all things to all people at all times.

JAMA Diagnostic Test Interpretation

Tilt Table Testing

William P. Cheshire, MD; Daniel V. Dudenkov, MD; Bala Munipalli, MD
Abstract Full Text
has active quiz
JAMA. Published online April 11, 2024. doi:10.1001/jama.2024.0004

This Diagnostic Test Interpretation uses a patient case to illustrate tilt table testing, useful for evaluating patients with syncope of unknown cause or postural orthostatic tachycardia syndrome (POTS).

JAMA Revisited

Medicine and Meteorology

Abstract Full Text
free access
JAMA. Published online April 11, 2024. doi:10.1001/jama.2023.18277
JAMA Patient Page

Flat Head Syndrome in Infants

Geisel R. Collazo, MD; Maria Isabel Angulo, MD
Abstract Full Text
free access
JAMA. Published online April 11, 2024. doi:10.1001/jama.2023.26048

This JAMA Patient Page describes the types of flat head syndrome and its prevention and treatment.

April 10, 2024
Research Letter

Intravascular Microaxial Left Ventricular Assist Device Manufacturer Payments to Cardiologists and Use of Devices

Sanket S. Dhruva, MD, MHS; Joseph S. Ross, MD, MHS; Michael A. Steinman, MD; et al.
Abstract Full Text
JAMA. Published online April 10, 2024. doi:10.1001/jama.2024.4682

This study examines whether payments from a left ventricular assist device manufacturer to cardiologists performing percutaneous coronary intervention were associated with any use of the devices.

Viewpoint

Including Pregnant and Lactating Women in Clinical Research: Moving Beyond Legal Liability

Margaret Foster Riley, JD
Abstract Full Text
free access
JAMA. Published online April 10, 2024. doi:10.1001/jama.2024.6874

This Viewpoint summarizes a new report from the National Academies of Sciences, Engineering, and Medicine that encourages the inclusion of pregnant and lactating individuals in clinical research.

JAMA Insights

Women's Health

Uterine Fibroids

Erica E. Marsh, MD, MSCI; Ganesa Wegienka, PhD; David R. Williams, PhD, MPH
Abstract Full Text
has active quiz
JAMA. Published online April 10, 2024. doi:10.1001/jama.2024.0447

This JAMA Insights in the Women鈥檚 Health series discusses the incidence, diagnosis, and treatment of uterine fibroids.

Poetry and Medicine

Sternotomy

Mitch Browne
Abstract Full Text
free access
JAMA. Published online April 10, 2024. doi:10.1001/jama.2024.0496
Correction

Consortium Authors and Nonauthor Collaborators Added

Abstract Full Text
free access
JAMA. Published online April 10, 2024. doi:10.1001/jama.2024.2984
April 8, 2024
Original Investigation

Single Ascending and Multiple-Dose Trial of Zerlasiran, a Short Interfering RNA Targeting Lipoprotein(a): A Randomized Clinical Trial

Steven E. Nissen, MD; Kathy Wolski, MPH; Gerald F. Watts, MD, DSc; et al.
Abstract Full Text
JAMA. Published online April 8, 2024. doi:10.1001/jama.2024.4504

This phase 1 randomized study assesses the safety and tolerability of zerlasiran, a short interfering RNA targeting hepatic synthesis of apolipoprotein(a), and its effects on serum concentrations of lipoprotein(a), in healthy participants and patients with stable atherosclerotic cardiovascular disease.

Research Letter

Cardiac Function Before Sepsis and Clinical Outcomes

Stuthi Iyer, MPH; Jason N. Kennedy, MS; Jacob C. Jentzer, MD; et al.
Abstract Full Text
JAMA. Published online April 8, 2024. doi:10.1001/jama.2024.3917

This cohort study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospitalization outcomes and mortality.

Viewpoint

Data Checks Before Registering Study Protocols for Health Care Database Analyses

Shirley V. Wang, PhD; Sebastian Schneeweiss, MD, ScD
Abstract Full Text
free access
JAMA. Published online April 8, 2024. doi:10.1001/jama.2024.2988

This Viewpoint discusses the challenges involved with secondary health care data collection vs primary data collection and provides a list of suggested data checks before registration of a study protocol using secondary data.

Review

Systemic Lupus Erythematosus: A Review

Caroline H. Siegel, MD, MS; Lisa R. Sammaritano, MD
Abstract Full Text
has active quiz has audio
JAMA. Published online April 8, 2024. doi:10.1001/jama.2024.2315

This review summarizes current evidence regarding the diagnosis, treatment, and prognosis of systemic lupus erythematosus.

  • Audio: Diagnosis and Treatment of Systemic Lupus Erythematosus
April 7, 2024
Original Investigation

Clinical Benefit and Regulatory Outcomes of Cancer Drugs Receiving Accelerated Approval

Ian T. T. Liu, MD, JD, MPH, MS; Aaron S. Kesselheim, MD, JD, MPH; Edward R. Scheffer Cliff, MBBS, MPH
Abstract Full Text
JAMA. Published online April 7, 2024. doi:10.1001/jama.2024.2396

This study aims to determine whether cancer drugs granted accelerated approval from the US Food and Drug Administration ultimately demonstrate clinical benefit and to evaluate the basis of conversion to regular approval.

Cancer Stage Compared With Mortality as End Points in Randomized Clinical Trials of Cancer Screening: A Systematic Review and Meta-Analysis

Xiaoshuang Feng, PhD; Hana Zahed, PhD; Justina Onwuka, PhD; et al.
Abstract Full Text
JAMA. Published online April 7, 2024. doi:10.1001/jama.2024.5814

This meta-analysis of 41 randomized clinical trials of cancer screening compares cancer-specific mortality with stage III-IV cancer as end points.

Editorial

Late-Stage Cancer End Points to Speed Cancer Screening Clinical Trials鈥擭ot So Fast

Peter B. Bach, MD, MAPP
Abstract Full Text
free access
JAMA. Published online April 7, 2024. doi:10.1001/jama.2024.5821
April 6, 2024
Original Investigation

Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial

Richard M. Martin, BM, BS, PhD; Emma L. Turner, PhD; Grace J. Young, MSc; et al.
Abstract Full Text
has audio
JAMA. Published online April 6, 2024. doi:10.1001/jama.2024.4011

This secondary analysis of a randomized clinical trial assesses whether screening for prostate-specific antigen reduces prostate cancer mortality at 15-year follow-up.

  • Audio: The Evolution of Screening Tools for Prostate Cancer
Preliminary Communication

Prostate Cancer Screening With PSA, Kallikrein Panel, and MRI: The ProScreen Randomized Trial

Anssi Auvinen, MD, PhD; Teuvo L. J. Tammela, MD, PhD; Tuomas Mirtti, MD, PhD; et al.
Abstract Full Text
has audio
JAMA. Published online April 6, 2024. doi:10.1001/jama.2024.3841

This preliminary descriptive report compares the rates of detecting high- and low-grade prostate cancer in men invited for prostate cancer screening vs those not invited to undergo prostate cancer screening.

  • Audio: The Evolution of Screening Tools for Prostate Cancer
Editorial

A Pragmatic Approach to Prostate Cancer Screening

Jeffrey J. Tosoian, MD, MPH; David F. Penson, MD, MPH; Arul M. Chinnaiyan, MD, PhD
Abstract Full Text
has audio
JAMA. Published online April 6, 2024. doi:10.1001/jama.2024.4089
  • Audio: The Evolution of Screening Tools for Prostate Cancer
April 4, 2024
Editorial

Introducing the JAMA Summit

Kirsten Bibbins-Domingo, PhD, MD, MAS; Derek C. Angus, MD, MPH; Hannah Park; et al.
Abstract Full Text
free access
JAMA. Published online April 4, 2024. doi:10.1001/jama.2024.5570
Comment & Response

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Patrick Schober, MD, PhD, MMedStat; Stephan Alexander Loer, MD, PhD, MSc; Lothar Andreas Schwarte, MD, PhD, MBA
Abstract Full Text
JAMA. Published online April 4, 2024. doi:10.1001/jama.2024.1417

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Romain Jouffroy, MD, PhD; Raquel Tena, MD; Benoît Vivien, MD, PhD
Abstract Full Text
JAMA. Published online April 4, 2024. doi:10.1001/jama.2024.1423

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Frédéric M. Jacobs, MD, MSc
Abstract Full Text
JAMA. Published online April 4, 2024. doi:10.1001/jama.2024.1426

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

Cheng-Han Chiang, MD; Tou-Yuan Tsai, MD; Yi-Kung Lee, MD, MPH
Abstract Full Text
JAMA. Published online April 4, 2024. doi:10.1001/jama.2024.1429

Noninvasive Airway Management of Comatose Patients With Acute Poisoning鈥擱eply

Yonathan Freund, MD, PhD; Ben Bloom, MD
Abstract Full Text
JAMA. Published online April 4, 2024. doi:10.1001/jama.2024.1432
April 3, 2024
Comment & Response

Metformin Plus Insulin for Preexisting Diabetes or Gestational Diabetes in Pregnancy

Fariba Pourkarim, PharmD; Taher Entezari-Maleki, PharmD
Abstract Full Text
JAMA. Published online April 3, 2024. doi:10.1001/jama.2024.1380

Metformin Plus Insulin for Preexisting Diabetes or Gestational Diabetes in Pregnancy鈥擱eply

Kim A. Boggess, MD; MOMPOD Study PIs
Abstract Full Text
JAMA. Published online April 3, 2024. doi:10.1001/jama.2024.1383
April 1, 2024
Original Investigation

Reducing Hospitalizations and Multidrug-Resistant Organisms via Regional Decolonization in Hospitals and Nursing Homes

Gabrielle M. Gussin, MS; James A. McKinnell, MD; Raveena D. Singh, MA; et al.
Abstract Full Text
free access has audio
JAMA. Published online April 1, 2024. doi:10.1001/jama.2024.2759

This quality improvement study evaluates whether implementation of a decolonization collaborative is associated with reduced regional multidrug-resistant organism prevalence, incident clinical cultures, infection-related hospitalizations, costs, and deaths.

  • Audio: Regional Interventions to Prevent Multidrug-Resistant Organisms
Editorial

Controlling Multidrug-Resistant Organisms Across Patient-Sharing Networks

Christopher J. Crnich, MD, PhD
Abstract Full Text
free access
JAMA. Published online April 1, 2024. doi:10.1001/jama.2024.0267

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Integrated Hepatitis C鈥揙pioid Use Disorder Care Through Facilitated Telemedicine: A Randomized Trial
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Differences in Donor Heart Acceptance by Race and Gender of Patients on the Transplant Waiting List
Original Investigation | April 23, 2024
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