Matthew W. Martinez, MD; Andrew M. Tucker, MD; O. Josh Bloom, MD, MPH; et al.
free access
JAMA Cardiol. 2021;6(7):745-752. doi:10.1001/jamacardio.2021.0565
This cross-sectional study compiles data from multiple North American professional sports teams to assess the prevalence of detectable inflammatory heart disease in professional athletes with prior coronavirus disease 2019 infection.
Katharina Mayer, MD; Ralph Hein-Rothweiler, MD; Stefanie Schüpke, MD; et al.
free access
JAMA Cardiol. 2021;6(7):753-761. doi:10.1001/jamacardio.2021.0475
This randomized clinical trial evaluates the efficacy and safety of revacept, a novel, lesion-directed antithrombotic drug, acting as a competitive antagonist to platelet glycoprotein VI.
Andrew J. Boyle, MBBS, PhD; Carl Schultz, MBChB, DPhil; Joseph B. Selvanayagam, MBBS, DPhil; et al.
free access
JAMA Cardiol. 2021;6(7):762-768. doi:10.1001/jamacardio.2021.0676
This randomized clinical trial assesses whether inhibition of calcium/calmodulin-dependent protein kinase II delta after myocardial infarction prevents left ventricular remodeling.
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Invited Commentary
To Be or Not to Be a CaMKII Inhibitor?
Mark E. Anderson, MD, PhD
JAMA Cardiol
Thomas Nestelberger, MD; Jasper Boeddinghaus, MD; Pedro Lopez-Ayala, MD; et al.
free access
JAMA Cardiol. 2021;6(7):771-780. doi:10.1001/jamacardio.2021.0669
This international, multicenter prospective diagnostic study tests whether novel cardiovascular biomarkers quantifying different pathophysiological pathways involved in type 2 and/or type 1 myocardial infarction may aid physicians in the rapid discrimination of these 2 types of myocardial infarction.
Michelle T. Lee, MD, PharmD; Dhruv Mahtta, DO, MBA; David J. Ramsey, PhD; et al.
free access
JAMA Cardiol. 2021;6(7):782-790. doi:10.1001/jamacardio.2021.0683
This study evaluates sex-based differences in antiplatelet agents, any statin, high-intensity statin therapy, and statin adherence in patients with premature and extremely premature atherosclerotic cardiovascular disease.
Ehete Bahiru, MD; Boback Ziaeian, MD, PhD; Corrina Moucheraud, ScD; et al.
free access
JAMA Cardiol. 2021;6(7):791-800. doi:10.1001/jamacardio.2021.0611
This cohort study evaluates the association between the proportion of dual-eligible beneficiaries for Medicare and Medicaid with heart failure quality of care and outcomes.
Thomas A. Zelniker, MD, MSc; Itamar Raz, MD; Ofri Mosenzon, MD, MSc; et al.
free access
JAMA Cardiol. 2021;6(7):801-810. doi:10.1001/jamacardio.2021.0660
This secondary analysis of a randomized clinical trial evaluates the relative safety and efficacy of dapagliflozin vs placebo by assessing risks of a composite of cardiovascular death and hospitalization for heart failure and of major adverse cardiovascular events according to baseline estimated glomerular filtration rate and urinary albumin to creatinine ratio in patients with type 2 diabetes.
Brandon Chalazan, MD; Denise Mol, BA; Faisal A. Darbar, BSc; et al.
free access
has audio
JAMA Cardiol. 2021;6(7):811-819. doi:10.1001/jamacardio.2021.0994
This cohort study describes comprehensive sequencing of 60 candidate atrial fibrillation genes in African American and Hispanic/Latinx probands to examine the combined prevalence of rare pathogenic variants and assess genotype-phenotype associations.
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Audio Author Interview:
Association of Rare Genetic Variants and Early-Onset Atrial Fibrillation in Ethnic Minority Individuals
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Editor's Note
Genetic Studies of Atrial Fibrillation in Diverse Cohorts and Identification of Diverse Phenotypes Associated With Single Genes
Sadiya S. Khan, MD, MSc; Elizabeth M. McNally, MD, PhD
JAMA Cardiol
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Audio Author Interview:
Association of Rare Genetic Variants and Early-Onset Atrial Fibrillation in Ethnic Minority Individuals
Afifah Mohamed, DPhil; Maciej Marciniak, MSc; Wilby Williamson, MBBS, DPhil; et al.
open access
JAMA Cardiol. 2021;6(7):821-829. doi:10.1001/jamacardio.2021.0961
This study investigates whether changes observed in left ventricular structure and function in preterm-born adults make them more susceptible to cardiac remodeling in association with blood pressure elevation.