Stephen Salloway, MD; Spyros Chalkias, MD; Frederik Barkhof, MD; et al.
open access
ÁñÁ«ÊÓƵ Neurol. 2022;79(1):13-21. doi:10.1001/jamaneurol.2021.4161
This secondary analysis of 2 phase 3 randomized clinical trials describes the radiographic and clinical characteristics of amyloid-related imaging abnormalities that occurred in the EMERGE and ENGAGE trials.
Thanh N. Nguyen, MD; Mohamad Abdalkader, MD; Simon Nagel, MD; et al.
open access
has active quiz
ÁñÁ«ÊÓƵ Neurol. 2022;79(1):22-31. doi:10.1001/jamaneurol.2021.4082
This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.
Maria C. Gonzalez, MD; Nicholas J. Ashton, PhD; Bárbara Fernandes Gomes, MSc; et al.
free access
has audio
ÁñÁ«ÊÓƵ Neurol. 2022;79(1):32-37. doi:10.1001/jamaneurol.2021.4222
This cohort study measures the concentrations of plasma p-tau (p-tau181 and p-tau231) and evaluates their associations with cognitive decline in individuals with probable dementia with Lewy bodies.
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Audio Author Interview:
Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Probable Dementia With Lewy Bodies
Juan María Sanchez-Caro, MD; Iñigo de Lorenzo Martínez de Ubago, MD; Elena de Celis Ruiz, MD; et al.
free access
has active quiz
ÁñÁ«ÊÓƵ Neurol. 2022;79(1):38-47. doi:10.1001/jamaneurol.2021.3989
This systematic review and individual participant meta-analysis examines factors associated with incident lobar intracerebral hemorrhage and death in patients with cerebral amyloid angiopathy–associated transient focal neurological episodes.
Rik Ossenkoppele, PhD; Ellen H. Singleton, MS; Colin Groot, PhD; et al.
open access
ÁñÁ«ÊÓƵ Neurol. 2022;79(1):48-60. doi:10.1001/jamaneurol.2021.4417
This systematic review and meta-analysis reviews literature on the behavioral variant of Alzheimer disease and uses the outcomes to propose research criteria for this syndrome.
Kazunori Toyoda, MD, PhD; Sohei Yoshimura, MD, PhD; Michikazu Nakai, PhD; et al.
open access
ÁñÁ«ÊÓƵ Neurol. 2022;79(1):61-69. doi:10.1001/jamaneurol.2021.4346
This cohort study assesses secular changes in initial neurological severity and short-term functional outcomes of patients with acute stroke by sex using a large population.
Alexandra Astner-Rohracher, MD; Georg Zimmermann, PhD; Tamir Avigdor, MSc; et al.
free access
ÁñÁ«ÊÓƵ Neurol. 2022;79(1):70-79. doi:10.1001/jamaneurol.2021.4405
This cohort study identifies predictors for focality of the seizure-onset zone in stereoelectroencephalography based on standard presurgical epilepsy investigation to develop a score to calculate the probability of identifying a focal seizure onset in stereoelectroencephalography.