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Year

Day

March 28, 2024
Original Investigation

Neoadjuvant Dual Checkpoint Inhibitors vs Anti-PD1 Therapy in High-Risk Resectable Melanoma: A Pooled Analysis

Abstract Full Text
open access
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2023.7333

This pooled analysis of 6 clinical trials describes the safety and efficacy of different courses of immune checkpoint inhibitor treatment in a neoadjuvant setting among patients with high-risk resectable melanoma.

Tumor Intrinsic Subtypes and Gene Expression Signatures in Early-Stage ERBB2/HER2-Positive Breast Cancer: A Pooled Analysis of CALGB 40601, NeoALTTO, and NSABP B-41 Trials

Abstract Full Text
open access
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2023.7304

This retrospective analysis of data from 3 randomized clinical trials examines the association of pathologic complete response with event-free survival by intrinsic subtype and other gene expression signatures in patients with ERBB2/HER2-positive early breast cancer treated in the neoadjuvant setting

Brief Report

Machine Learning–Based Prediction of Hospitalization During Chemoradiotherapy With Daily Step Counts

Abstract Full Text
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2024.0014

This study develops and validates machine learning approaches based on daily step counts collected by wearable devices in 3 prospective trials to predict hospitalizations during chemoradiotherapy.

Physical Activity Using a Wearable Device as an Alternative to Performance Status in Patients With Advanced Lung Cancer

Abstract Full Text
open access
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2024.0023

This cohort study investigates the association between measured physical activity and Eastern Cooperative Oncology Group Performance Status, as well as the potential prognostic value of physical activity measurements in patients with advanced lung cancer.

Editorial

The Potential of Wearable Devices in Cancer Care Delivery

Abstract Full Text
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2024.0001
JAMA Oncology Patient Page

Cancer Care in the Era of Artificial Intelligence

Abstract Full Text
free access
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2023.7263

This JAMA Oncology Patient Page explains artifical intelligence and what patients should know about how it can be used in oncology.

Cancer Care Chronicles

Dog Aloisanov Helped Diagnose My Cancer

Abstract Full Text
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2024.0186

This essay describes how a dog played a role in one physicians process of being diagnosed with hepatocellular carcinoma.

Comment & Response

Comment on Cancers Attributable to Infections in the US

Abstract Full Text
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2024.0225

Comment on the Burden of Infection-Attributable Cancers in the US

Abstract Full Text
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2024.0222

Comment on the Burden of Infection-Attributable Cancers in the US—Reply

Abstract Full Text
JAMA Oncol. Published online March 28, 2024. doi:10.1001/jamaoncol.2024.0228
March 21, 2024
Original Investigation

Neoadjuvant Chemoimmunotherapy for NSCLC: A Systematic Review and Meta-Analysis

Abstract Full Text
open access
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0057

This meta-analysis investigates the association of neoadjuvant chemoimmunotherapy with patient benefits vs neoadjuvant chemotherapy in patients with non–small cell lung cancer (NSCLC).

Brief Report

Analysis and Optimization of Equitable US Cancer Clinical Trial Center Access by Travel Time

Abstract Full Text
open access has audio
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2023.7314

This study investigates the geographical distribution of self-identified racial and socioeconomic demographics within commuting distance to cancer clinical trial centers and other hospitals.

Review

PARP Inhibitors for Breast Cancer Treatment: A Review

Abstract Full Text
has active quiz
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2023.7322

This narrative review summarizes the literature supporting the use of poly(adenosine diphosphate–ribose) polymerase (PARP) inhibitors for breast cancer treatment, as well as potential future research directions.

Viewpoint

The Ethics of Hope—A Moral Imperative for Oncologists

Abstract Full Text
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0011

This Viewpoint suggests that giving patients with terminal cancer unrealistic hope based only on cure is ethically inferior to redirecting patients toward noncurative goals and noncancer-related hope.

Editorial

JAMA Oncology—The Year in Review, 2023

Abstract Full Text
free access
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0153

The Chemoimmunotherapy Revolution in Resectable NSCLC—The Times They Are A-Changin’

Abstract Full Text
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0043
Poetry and Oncology

Nonverbal

Abstract Full Text
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2023.7330
Comment & Response

The SOUND Randomized Clinical Trial Results

Abstract Full Text
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0122

The SOUND Randomized Clinical Trial Results

Abstract Full Text
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0125

The SOUND Randomized Clinical Trial Results

Abstract Full Text
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0128

The SOUND Randomized Clinical Trial Results—Reply

Abstract Full Text
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0131
Peer Reviewers List

JAMA Oncology Peer Reviewers in 2023

Abstract Full Text
free access
JAMA Oncol. Published online March 21, 2024. doi:10.1001/jamaoncol.2024.0167
March 14, 2024
Original Investigation

Noninferiority of Hypofractionated vs Conventional Postprostatectomy Radiotherapy for Genitourinary and Gastrointestinal Symptoms: The NRG-GU003 Phase 3 Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. Published online March 14, 2024. doi:10.1001/jamaoncol.2023.7291

This randomized clinical trial aims to determine if hypofractionated postprostatectomy radiotherapy is noninferior to conventionally fractionated postprostatectomy for patient-reported genitourinary (GU) and gastrointestinal (GI) symptoms at 2 years.

Research Letter

Patterns of Undertreatment and Overtreatment in Adjuvant Radiotherapy for Early-Stage Endometrial Cancer Based on Molecular Classification

Abstract Full Text
JAMA Oncol. Published online March 14, 2024. doi:10.1001/jamaoncol.2024.0104

The quality improvement study examines the use of risk-adaptive adjuvant radiotherapy in women with non–mismatch repair deficiency endometrial cancer.

Viewpoint

Unveiling the Untapped Potential of Antibody Drug Conjugates in Precision Oncology

Abstract Full Text
JAMA Oncol. Published online March 14, 2024. doi:10.1001/jamaoncol.2024.0008

This Viewpoint discusses cancer antigen expression and antibody drug conjugates.

Invited Commentary

Hypofractionation for Postprostatectomy Radiotherapy

Abstract Full Text
JAMA Oncol. Published online March 14, 2024. doi:10.1001/jamaoncol.2023.6697
Comment & Response

Quantification of Treatment Effect of Tislelizumab vs Sorafenib for Hepatocellular Carcinoma

Abstract Full Text
JAMA Oncol. Published online March 14, 2024. doi:10.1001/jamaoncol.2024.0116

Health and the 2024 US Election

Quantification of Treatment Effect of Tislelizumab vs Sorafenib for Hepatocellular Carcinoma—Reply

Abstract Full Text
JAMA Oncol. Published online March 14, 2024. doi:10.1001/jamaoncol.2024.0119
March 7, 2024
Original Investigation

Stereotactic Radiation Therapy in Early Non–Small Cell Lung Cancer and Interstitial Lung Disease: A Nonrandomized Clinical Trial

Abstract Full Text
JAMA Oncol. Published online March 7, 2024. doi:10.1001/jamaoncol.2023.7269

This nonrandomized clinical trial examines the toxicity and efficacy of stereotactic ablative radiotherapy in patients with interstitial lung disease and early-stage non–small cell lung cancer.

Efficacy and Safety of Radiotherapy Plus Relugolix in Men With Localized or Advanced Prostate Cancer

Abstract Full Text
open access
JAMA Oncol. Published online March 7, 2024. doi:10.1001/jamaoncol.2023.7279

This study examines 2 randomized clinical trials to assess the efficacy and safety of the oral gonadotropin-releasing hormone antagonist relugolix with radiotherapy for treating prostate cancer.

Viewpoint

Charting the Path to Systemic Therapy De-escalation—Oligometastatic Kidney Cancer as a Paradigm

Abstract Full Text
JAMA Oncol. Published online March 7, 2024. doi:10.1001/jamaoncol.2023.7266

This Viewpoint discusses whether select patient populations may benefit from de-escalation rather than escalation of systemic therapy for kidney cancer.

Invited Commentary

Prospective Data on Stereotactic Ablative Radiotherapy Provides Guidance in an Unusual Clinical Scenario

Abstract Full Text
JAMA Oncol. Published online March 7, 2024. doi:10.1001/jamaoncol.2023.7039
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