This multicenter randomized clinical trial examines the effectiveness and safety of left atrial appendage ligation plus pulmonary vein isolation for nonparoxysmal atrial fibrillation treatment.
This study assesses whether participants with anomalous health incidents (AHIs) differ significantly from US government control participants with respect to clinical, research, and biomarker assessments.
This study assesses whether participants with anomalous health incidents (AHIs) differ significantly from US government control participants with respect to magnetic resonance imaging鈥揹etectable brain lesions.
This study of patients with early-stage triple-negative breast cancer not treated with adjuvant or neoadjuvant chemotherapy analyzes the association between tumor-infiltrating lymphocyte levels, cancer recurrence, and survival.
This study compares outcomes of surgery and functional bracing for closed humeral shaft fractures after 5 years of follow-up.
This study estimates public and private spending on genetically targeted treatments for Duchenne muscular dystrophy during years in which the drugs were marketed without completed confirmatory studies.
This Viewpoint discusses the Alabama Supreme Court鈥檚 opinion on in vitro fertilization and how it plays into a larger push for fetal and embryonic personhood.
This Viewpoint breaks down the myriad ways the Alabama Supreme Court decision to declare frozen embryos as legal equivalents to children harms the health of mothers and fetuses, limits reproductive decision-making based on genetics and out-of-reach costs, and impedes research.
This Viewpoint discusses contemporary approaches to mentoring and coaching new physicians.
This Viewpoint discusses lecanemab use and the risk of cerebral macrohemorrhage for patients with mild cognitive impairment or early dementia.
In this narrative medicine essay, a medical student participating in a study learns she has Lynch syndrome, setting off a cascade of emotions of dread, fear, and some hope in diagnostic plans and future breakthroughs in cancer treatment.
This JAMA Clinical Guidelines Synopsis summarizes the Endocrine Society鈥檚 2023 recommendations on management of outpatients with diabetes and high risk of hypoglycemia.
A patient had burning and pain in the mouth, reduced oral aperture, white-tan plaques on the oral mucosa, and thickened buccal mucosae bilaterally; biopsy of the lower labial mucosa showed subepithelial fibrosis. She had no history of cigarette smoking or use of chewing tobacco but had current and past history of chewing areca nuts. What is the diagnosis and what would you do next?
This Medical News story discusses questions about multiple cancer early detection tests, 2 of which are already on the US market.
This Arts and Medicine feature reviews the clinical and neurophysiologic features of earworms, music fragments heard in the mind that repeat over and over as if jammed in playback mode.
This JAMA Patient Page describes solar eclipses and how to view them safely.